OS X 10.4 comes with python 2.3.5 and wx 2.5.3.1 installed.  The bad news is
that both are way out of date. The good news is that upgrading them is easy.

1. Download dmg's for the current versions of both python and wx. The download
links for the current versions are http://www.python.org/download/ and
http://www.wxpython.org. As of 12 Feb 2007 you would be downloading python 2.5:

	python-2.5-macosx.dmg 

and wx 2.8.1.1:

	wxPython2.8-osx-unicode-2.8.1.1-universal10.4-py2.5.dmg

2. Install the dmg's as usual.

3. So that the new version of python and wx will be found open ~/.bash_profile
with a text editor and add the lines

PATH="/Library/Frameworks/Python.framework/Versions/Current/bin:${PATH}"
export PATH

at the end of the file to prepend the path to the new version of python to 
your existing path.

4. Testing: Log out and back in again, open a terminal window and enter

$ python

You should have gotten "Python 2.5" as the first line of output. You are now
in a python shell. Enter

>>> import wx
>>> wx.__version__

You should get '2.8.1.1'.  You can now enter Ctrl-D to exit and you're good
to go.