CURRICULUM VITAE
Bruce Maurice
Klitzman
PERSONAL
INFORMATION
Address: (office): Kenan Plastic Surgery Research Laboratories
Duke
University Medical Center
P.
O. Box 3906, room 0019 Research Park 4
Durham,
North Carolina 27710-3906
(home): 3015
Wade Rd.
Durham,
North Carolina 27705‑5630
Telephone: (office):
(919) 684‑3929/684-6686 [fax
(919) 681-2670]
email:klitz@duke.edu http://www.duke.edu/~klitz
(home): (919) 489‑0680
Birth Date: November
4, 1951 Birthplace: Dayton, Ohio Citizenship: USA
Marital Status: Married, Hardee Brown
Klitzman Children: Rachel 10/10/83;
Page 9/3/88
EDUCATION
University of Virginia, Charlottesville,
VA: Ph.D., 1979, Physiology: Microvascular Determinants
of Oxygen Supply in Resting and
Contracting Striated Muscle; Advisor, Brian R. Duling
Duke University, Durham, N.C.
27706: B.S.E. cum laude,
1974, Biomedical Engineering
APPOINTMENTS
Research Associate in Physiology,
University of Arizona College of Medicine, 1979‑1981;
Chairman: Paul Johnson, Ph.D.
Assistant Professor of Physiology and
Biophysics, Louisiana State University School of
Medicine in Shreveport, 1981‑1985
APPOINTMENTS
(cont.)
Adjunct Assistant Professor
of Biomedical Engineering, Louisiana Tech University, 1982‑1986
Associate Professor
of Physiology & Biophysics (tenured), Louisiana State University
School of Medicine in Shreveport,
1985
Senior Director,
Plastic Surgery Research Laboratories, and Assistant Research Professor of
Surgery (Division of Plastic,
Reconstructive, Maxillofacial, and Oral Surgery) and
Cell Biology (Division of
Physiology), Duke University Medical Center, 1985-; Associate
Professor of Biochemical
Engineering, 1994-2000; Associate Research Professor of
Surgery 2005-
Member, Center for
Cellular and Biosurface Engineering, Duke University, 1995-2002
Member,
Comprehensive Cancer Center, Duke University, 1999-
Assistant Research
Professor of Biomedical Engineering, Duke University, 2000-
Member and Steering
Committee Member, Center for Biomolecular and Tissue Engineering,
Duke University , 2002-
ACTIVE RESEARCH AWARDS
Research Grant, NIH R01 CA40355, M
Dewhirst, principal investigator; B. Klitzman,
Co-investigator, "Heat and
radiation effects in tumor microcirculation", 2004-2009
Program Project Grant, NIH P01 CA42745, M
Dewhirst, PI. B. Klitzman, investigator
"Hyperthermia and perfusion
effects in cancer therapy ".
1990-2005
Research Grant, NIH R01DK54932, WM
Reichert, principal investigator; B. Klitzman,
Co-investigator, "Biosensor
biocompatibility", 1998-2008
Research Grant, Kinetic Concepts, Inc., B. Klitzman, PI.
“Effects of VAC therapy on wound
metabolites”, 2004-2005
Research Grant, Nitrox L.L.C., B. Klitzman, PI.
“Reversal of vasospasm with ENO”,
2004-2005
HONORS AND AWARDS
Fellow, NATO: Advanced Study Institute
on Biorheology, Houston, TX, 1980
Travel Award, European Society for
Microcirculation, September, 1980
Invited Lecturer, Gordon Research Conference
on "Water and Solute Exchange in the
Microvasculature", June 1982
Travel Grant, NRC/APS, XXIX IUPS Congress,
Sydney, 1983
Keynote Speaker, Australia/New Zealand Symp.
on Microcirculation, Leura, Aust.,1983
Fellow, Council on Circulation, American
Heart Association, 1984-present
HONORS AND
AWARDS (cont.)
Chairman, Vascular Organization, Third World
Congress for Microcirculation, 1984
Cardiovascular and Renal Study Section, NIH,
Ad hoc Reviewer, 1985
Burroughs‑Wellcome Visiting Scientist,
1985
Special Study Section, NIH Public Advisory
Group, 1986
First Prize, Basic Science Award, Am. Assoc.
Hand. Surg., 1986
Chairman, Laser session, Fourth World
Congress for Microcirculation, 1987
First Prize, Basic Science Award, Am. Assoc.
Hand. Surg. 1987
First Prize, Investigator Category, Plastic
Surgery Educational Foundation, 1988
First Prize, Basic Science Award, Am. Assoc.
Hand. Surg. 1988
Hearing Research Study Section, NIH, Guest
Reviewer, 1989
Chairman, Bioengin. of Heart and Circ.,
Biomed. Engineer. Soc./FASEB, 1990
Surgery Anesthesiology and Trauma Study
Section, NIH, Guest Reviewer, 1990
Chairman, Symposium on "Thrombosis and
Microvascular Surgery", Fifth World
Congress for Microcirculation,
Louisville, KY, 1991
Chairman, "Laser Doppler
Flowmetry" Symposium, FASEB, 1992
Research Mentor, Howard Hughes Research
Award, 1991-2
First Prize, Senior Author and Mentor, Univ.
North Carolina at Chapel Hill,
Machiko-Kuno Medical Student
Research Award, 1992
Executive Committee, Microcirculatory
Society, 1993-2000
Secretary, The Microcirculatory Society,
1993-97
Resident Competition Awardee, Sr. Author,
Undersea and Hyperbaric Med Soc, 1993
Research Supervisor, Howard Hughes Fellow,
1994-5
HONORS AND
AWARDS (cont.)
Visiting Professor, Chang Gung Memorial
School of Medicine, Taipei, Taiwan, 1994
Listed in Who's Who; Who's Who in America; Who's Who in the World; Who's Who in
American
Education;
Who's Who in the South and Southwest
First Prize, Senior Author and Mentor,
Society for Biomaterials, Outstanding Paper Award, 1995
President-elect, The Microcirculatory
Society, 1997-8
Program Committee, Experimental Biology '98
(FASEB), 1998
Scientific Advisory Board, Plastic Surgery
Research Council, 1998
Founder, North Carolina Tissue Engineering
Interest Group, 1998
Chair, “Tissue Engineering: Designer organs
are on their way”. Symposium at Biotech ’98,
NC
Biotechnology Center, 1998
Program Committee, Plastic Surgery Research
Council, 1998
Chair, “Vascular development in engineered
tissues”, Symposium at
Experimental Biology ’98,1998
President, The Microcirculatory Society,
1998-99
First Prize, Basic Science Paper,
Southeastern Soc. Plast. Reconstr. Surg., 1998
Best Paper Award, Musculoskeletal Infection
Soc., Co-author, 1998
Third Prize, Investigator Category, Plastic
Surgery Educational Foundation, 1999
Chair, “Tissue Repair and Regeneration”
Symposium at Biotech 2000,
Council
for Entrepreneurial Development, Chapel Hill, NC, 2000
Featured Speaker, First World Society for
Reconstructive Microsurgery, Taipei, Taiwan, 2001
Member, International Liaison Committee for
Societies of Microcirculation, 2001-2006
NIH Public Advisory Group (Study Section),
2002, 2003
HONORS AND
AWARDS (cont.)
Chair, Experimental Forum, World Society for
Reconstructive Microsurgery,
Heidelberg, Germany, 2003
Best Paper Award (senior author), World
Society for Reconstructive Microsurgery,
Heidelberg, Germany, 2003
EDITORIAL BOARDS
BOARD MEMBER
Journal
of Reconstructive Microsurgery, Associate
Editor for Basic Science, 1986-1996
Cell
Transplantation, Editorial Board, 1995-
Microcirculation, Editorial Board, 1998-2002
Microvascular
Research, Editorial Board, 1999-
GUEST REVIEWER
American
Journal of Physiology, several sections
Annals
of Biomedical Engineering
Blood Vessels
Circulation
Research
Journal of
Applied Physiology
Journal
of Investigative Dermatology
Journal
of Laboratory and Clinical Medicine
Journal of
Orthopaedic Research
Journal of
Physiology
International
Journal of Radiation Research
International
Journal of Hyperthermia
Laboratory
Investigation
Life
Sciences
Microcirculation
Microsurgery
Microvascular
Research
Pflüger's
Archiv, European Journal of Physiology
Plastic and
Reconstructive Surgery
Radiation
Research
Tissue
Engineering
PROFESSIONAL
SOCIETIES
American Physiological Society
The Microcirculatory Society (Secretary,
1993-7; President-elect, 1997-8; President, 1998-9)
European Society for Microcirculation
(Travel Awardee, 1980)
American Heart Association; Fellow, Council
on Circulation
Society for Biomaterials
International Society for Oxygen Transport
to Tissue
Plastic Surgery Research Council (Senior
Member; Scientific Advisory Board, 1998)
American Society for Reconstructive
Microsurgery
Society for Tissue Engineering, charter member
North Carolina Tissue Engineering Interest
Group, Founder
European Society for Tissue Engineering
TEACHING EXPERIENCE
1974‑1979 University of Virginia: Discussion and
laboratory sections for medical students; lectures and laboratory sections in
Physiology for graduate nursing students.
1979‑1981 University of Arizona: Lectures,
discussion, and laboratory sections in Cardiovascular Physiology to medical
students: Lectures and labs in Physiology for engineers.
1982‑1985 Louisiana State University: Lectures
in Cardiovascular Physiology to medical students and to Allied Health
students. Lectures in Cell Biology to Graduate students.
1986- Duke University School of Medicine: Lectures and laboratories in Cardiovascular
Physiology for medical students.
Director of computer simulation laboratories for medical students.
Preceptor for nine-month research experience for medical students. Lectures in Cardiovascular Physiology to
graduate students. Lectures in graduate
Cell Biology course in Mechanisms of Cell Injury. Lectures in Biomedical Engineering, various graduate and
undergraduate courses. Graduate Course
(Director) in Advanced Microvascular Mass Transport. Undergraduate and graduate independent studies.
POST-DOCTORAL FELLOWS AND VISITING
PROFESSORS SUPERVISED .
1987-88 Bryan Forley
1988-89 Edmond Ritter
1989-91 Kyung Won Minn, James Cronan
1990-92 Mohammed Fata, Yong Bae Kim, Tim Mo
Chen
1992-93 Sang Yeul Lee
1993-95 Magdy El Sayed Ali Hussein, Elena
Marincea
1995-97 Chih-Hung Lin, Ayman Nabawi, Hye
Kyung Lee
1996-98 Jong-Won Rhie
1997-98
Lior Heller
1997-99 Sameir Sulliman, Al-Moddather M.
El-Hadidy
1999-2000 Kevin Olbrich
2001-02 Koji Yasui, Christoph Heitmann
2003-04 Yuji Kondo
2004-05 Ahmed El-Sabbagh
DISSERTATION
COMMITTEES
1980-4 Kevin Dellsperger Physiology Louisiana
State University
1990-2 Yi-Chang Wu Cell
Biology Duke University
1990-1 ChristopherForrest (Masters) Pharmacology University of Toronto
1991-3 Richard Malinhauskas Biomed. Engin. Duke
University
1992-5 Paul Fisher Cell
Biology Duke University
1993-6 Tracey du Laney Biomed.
Engin. Duke University (co-Advisor)
1993-6 Robert Herrmann Biomed.
Engin. Duke University
1993-7 Yao Xiao Biomed.
Engin. Duke University
1993-5 Jing Zhang Cell
Biology Duke University
1994-7 Adam Sharkawy Biomed.
Engin. Duke University (co-Advisor)
1994-7 Marlene Hauck Pathology Duke University
DISSERTATION
COMMITTEES (cont.) .
1996-8 Vinayak Bhat Biomed. Engin. Duke
University (co-Advisor)
1997-8 Richard Hopper (Masters)
Pharmacology University of Toronto
1997-2001 Natalie Wisniewski Biomed.
Engin. Duke University (co-Advisor)
2000-03 John Alcorn Cell Biology Duke
University
2001-04 Lori Norton Biomed. Engin. Duke
University (co-Advisor)
2001-03 Bernard Chan Biomed. Engin. Duke
University
2002- Heather Prichard Biomed. Engin. Duke University (Advisor)
MEDICAL STUDENT ACADEMIC YEAR RESEARCH
SUPERVISED
1985-6 Jack Gelman
1986-7 Robert Burk, Stephen Chang, Marc
Goldberg, William Panza
1987-8 Willis Eshbaugh, Barbara Perona
1988-9 Mac Axelrod, Kim Koger, Katherine Young
1989-90 Michael
Cuffe, Edwin Page
1990-91 Andrew Fisher
1991-92 David Scher (Howard Hughes
Fellowship), Mark Wigod
1992-93 Albert Sam, Marya Sonny
1993-94 Michael Gimbel, Douglas Skarada
1994-95 Gregory Galdino, Thomas Steele,
Douglas Skarada (Howard Hughes Fellowship)
1995-96 Burt Sundin
1998-99 Frederick Moore, Adam Ravin, Tanja
Schütz
1999-00 Bethlehem Gelaw, Lilian Evans, Nicole
Kramer, Christiane Poellmann
2000-01 Ranya Sweis
2001-02 Farah Khan
2002-03 Jason Ko
2003-04 Renita Butler
2005-06 Corey Dozier
2006-07 Blaine Mischen; Luke Hoagland
UNDERGRADUATE STUDENT INDEPENDENT STUDY
RESEARCH SUPERVISED
1990-1 Robin Ritnour
1992-3 Pablo Elizalde
1993-4 Kindra Warnecke, Geoffrey Erickson
1995-6 Janis Marie Taube
1996-7 Regina Carney, Sidney Glasofer,
Jonathan Mathy
1997-8 Lucas Rugani, Kristin Ann Faraguna
1999-00 Lisbet Avila
2000-01 Phat Giang, Lorrin Lee
2002-03 Andrea Buckwalter
2003-04 Lauren Kahn
2005-06 Liza McClellan
STATEMENT OF
RESEARCH INTERESTS
The primary basic science research
interests of our laboratory are in the area of physiological mechanisms of
maintaining substrate transport from blood to tissue. This broad topic
covers studies on whole animals, such as rats and mice, as well as studies on
whole organ, hemorheological, microvascular, cellular, ultrastructural, and
molecular levels. The current projects include:
1) control of blood flow and flow
distribution in the microcirculation;
2) the effects of synthetic and
biologic implants on substrate transport to tissues;
3) the physiological adaptation of
the microcirculation and mitochondria to chronic hypoxia, hyperoxia, or cold,
and the subsequent alteration in oxygen transport;
4) mathematical modeling of tissue
oxygen tension distribution and angiogenesis.
5)
tissue engineering; combining isolated cells with biomaterials to form
specialized composite structures for implantation, with particular emphasis on
endothelial cell physiology and its alteration by isolation and seeding on
biomaterials;
6) decreasing the thrombogenicity of
synthetic blood vessels and improving their overall performance and
biocompatibility;
7) the investigation of tissue
damage resulting from abnormal perfusion (e.g., relative ischemia, anoxia,
etc.) and therapies which minimize ischemic damage;
8) the abnormal development of tumor
microcirculation and its effect on tumor oxygenation;
9) measurement of tissue blood flow
and oxygenation as an indicator of tissue viability and functional potential;
10) development of biocompatible
materials for soft tissue reconstruction or augmentation;
11) molecular and cellular effects
of ultraviolet light on skin which can lead to cancer, and therapies which may
minimize damage;
12) wound healing in bone and soft
tissues, with special emphasis on the detection and treatment of infection and
its effects on healing.
13) improving the outflow facility
of ophthalmologic devices implanted to reduce elevated intraocular pressures
found in patients with glaucoma.
Future studies will continue to
focus on improving the biocompatibility of biosynthetic implants. Additional new emphasis may be placed on
investigating the effects of radiation on wound healing and methods of
minimizing the consequences of radiation exposure. Specific collaborations with faculty in Biomedical Engineering
include improving the biocompatibility of biosensors, surface modification of
implanted devices, and transplanting endothelial cells onto small diameter
synthetic vascular grafts.
PUBLICATIONS
(peer review
journals only; Dr. Klitzman’s publications have been cited 1,551 times as of
1/05)
1.
Gorczynski, R. J., B. Klitzman and
B.R. Duling. Interrelations between contracting striated muscle and
precapillary microvessels. Am. J. Physiol 235 (Heart Circ. Physiol.
(4):H494‑504, 1978.
2. Klitzman, B. and B.R.
Duling. Microvascular hematocrit and red cell flow in resting and
contracting striated muscle. Am. J.
Physiol 237 (Heart Circ. Physiol. 6):H481‑490, 1979.
3. Duling,
B. R. and B. Klitzman.
Local control of microvascular function: Role in tissue oxygen supply. Ann. Rev. Physiol. 42:373‑382,
1980.
4. Schmid‑Schoenbein,
H., B. Klitzman, and Johnson,
P. C. Vasomotion and blood hemorheology fluidity: Maintenance of
blood fluidity in the microvessels by rhythmic vasomotion. Bibl. Anat. 20:138‑143,
1981.
5. Wetter,
T., H. Schmid‑Schoenbein, P.C. Johnson, and B. Klitzman. Simultaneous variation in flow velocity and hematocrit
in skeletal muscle. Bibl. Anat. 20:237‑241,
1981.
6. Klitzman, B., and P.C. Johnson. Hematocrit,
diameter, red cell flux, velocity and flow: Correlations and heterogeneities in
striated muscle capillaries. Bibl. Anat. 20:144‑149,
1981.
7. Klitzman, B. and P.C.
Johnson. Capillary network geometry and red cell distribution in hamster
cremaster muscle. Am. J. Physiol 242
(Heart Circ. Physiol. 11):H211‑H219, 1982.
8. Klitzman, B., D.N. Damon, R.J.
Gorczynski and B.R. Duling. Augmented tissue oxygen supply during striated
muscle contraction in the hamster: Relative contributions of capillary
recruitment, functional dilation, and reduced tissue PO2. Circ. Res. 51:711‑721,
1982.
9. Klitzman, B., A.S. Popel and B.R.
Duling. Oxygen transport in resting and contracting hamster cremaster
muscles: Experimental and theoretical microvascular studies. Microvasc. Res. 25:108‑131,
1983.
10. Klitzman, B. and S.J.
Fronczak. Mitochondrial localization in hamster cremaster muscle. Oxygen
Transp. Tissue 6:695‑700, 1985.
11. Klitzman, B. Capillary red cell
distribution and its effect on oxygen transport. Prog. Microcirc. Res. 2:124‑131,
1984.
12. Fleming,
B. F., B. Klitzman, and W.O.
Johnson. Measurement of erythrocyte velocity using a periodic
differential detector. Am. J. Physiol 249:H899-H905,
1985.
13. Klitzman, B., R.S. Sepka, and D. Serafin. Effect of systemic hematocrit on rat skin
flap survival. Surg. Forum. 37:581-582,
1986.
PUBLICATIONS (cont.)
14. Gelman, J.,
J.V. Bartolome, S.D. Jenkins, D. Serafin, S.M. Schanberg, and B. Klitzman. Reduced cell death in skin flaps in rats treated with
difluoromethylornithine (DFMO). FASEB J. 1:474-477, 1987.
15. Jenkins, S.D.,
R.S. Sepka, W.J. Barwick, D. Serafin, and B.
Klitzman. Routine clinical use of laser Doppler flowmeter for monitoring of
free tissue transfers. J. Reconstr. Microsurg. 3:281-284, 1987.
16. Huang, L., C.
Privalle, D. Serafin, and B. Klitzman.
Scavengers of superoxide radical increase survival of skin flaps. FASEB
J. 1:129-133, 1987.
17. Klitzman, B. Microvascular determinants
of blood flow. J. Reconstr. Microsurg.
4:77-80, 1987.
18. Ball, R., D.
Serafin, and B. Klitzman. Effects of topical chlorpromazine on skin
flap survival. Surg. Forum 38:587-589,
1987.
19. Klitzman, B., R.S. Sepka, S.D. Jenkins,
C.P. Demas, W.J. Barwick, J. Waters, D. Serafin. Non-invasive and invasive use of laser Doppler flowmeter for
evaluation of free tissue transfers. Microcirculation 1:368-369, 1987.
20. Klitzman, B., K. Oothout, and D.
Serafin. Beneficial effects of
prostanoids on rat skin flap survival. Microcirculation 1:765-766, 1987.
21. Demas, C.P.,
R.S. Sepka, R.D. Vann, B. Klitzman,
and W.J. Barwick. Decreased thrombogenicity of vascular prostheses following
gas denucleation. Plast. Reconstr. Surg. 82:1042-1046, 1988.
22. Forley, B.G.,
D. Serafin, and B. Klitzman. The potential role of
difluoromethylornithine in the treatment of keloids. Surg. Forum 39:550-553, 1988.
23. Ritter, E.F.,
R.D. Vann, C.W. Wyble, W.J. Barwick, and B.
Klitzman. Hydrostatic pressure
reduces thrombogenicity of polytetrafluoroethylene vascular grafts. Am. J.
Physiol 257:H1076-H1081, 1989.
24. Smith, Y.S., B. Klitzman, M.N. Ellis, F.C.
Kull. The effect of nicotinamide on
microvascular density and thermal injury in rats. J. Surg. Res.
47:465-469, 1989.
25. Burk, R.W. III,
D. Serafin, and B. Klitzman. Toxic effects of catecholamines on
skin. Plast. Reconstr. Surg. 85:92-99, 1990.
26. Young K.B., and
B. Klitzman. The effects of acute hyperbaric oxygen
therapy on axial pattern skin flap survival when administered during and after
total ischemia [Invited Discussion]. J.
Reconstr. Microsurg. 5:349-350,
1989.
PUBLICATIONS (cont.)
27. Serafin, D.,
W.C. Pederson, C. P. Demas, W.J. Barwick, and B. Klitzman. Microsurgical
composite tissue transplantation facilitated at a difficult recipient site by
creation of an arterio-venous fistula. Plast. Reconstr. Surg., 1990.
28. Eshbaugh, W.G.,
B.G. Forley, E.F. Ritter, J.V. Bartolome, D. Serafin, and B. Klitzman. Stimulation of
DNA synthesis in human epidermis by UV-B radiation and its inhibition by
difluoromethylornithine. Plast. Reconstr. Surg. 85:593-597, 1990.
29. Goldberg, J.,
R.S. Sepka, W.C. Pederson, M. Clinton, W.J. Barwick, D. Serafin, and B. Klitzman. Laser Doppler blood flow measurements of common cutaneous donor
sites for reconstructive surgery. Plast. Reconstr. Surg. 85:581-587, 1990.
30. Goldberg, M.,
D. Serafin, and B. Klitzman. Quantification of neutrophil adhesion to
venular endothelium following ischemia and reperfusion. J.
Reconstr. Microsurg. 6:267-270, 1990.
31. Axelrod, M.S.,
D. Serafin, and B. Klitzman. Ultraviolet light and skin cancer: An
immunogenic theory of epidermal carcinogenesis. Plast. Reconstr. Surg.
86:582-594, 1990.
32. Perona, B.P.,
R.S. Sepka, J.V. Bartolome, D. Serafin, and B. Klitzman. Acute
difluoromethylornithine treatment increases skin flap survival in rats. Ann.
Plast. Surg. 25:26-29, 1990.
33. Klitzman, B. Regional variations of
laser Doppler blood flow in ischemic skin flaps [Invited Discussion]. Plast. Reconstr. Surg. 85:327-328, 1990.
34. Minn, K.W., E.
Mikat, D. Serafin, and B. Klitzman. Microvenous reconstruction of rat femoral
veins with composite polyurethane prostheses.
Plast. Reconstr. Surg.
87:536-542, 1991.
35. Clinton, M.,
R.S. Sepka, D. Bristol, W.J. Barwick, W.C. Pederson, D. Serafin, and B. Klitzman. Establishment of normal ranges of laser Doppler blood flow in
autologous tissue transplants. Plast. Reconstr. Surg. 87:299-309, 1991.
36. Bensen, C.V.,
R.D. Vann, K.E. Koger, and B. Klitzman. Quantification of gas denucleation and
thrombogenicity of vascular grafts. J. Biomed. Mater. Res. 25:373-386, 1991.
37. Dewhirst, M.W.,
E.T. Ong, B. Klitzman, T.W. Secomb,
R.Z. Vinuya, R. Dodge, D. Brizel, and J.F. Gross. Perivascular oxygen tensions in a dorsal flap window
chamber. Rad. Res. 130:171-182, 1992.
38. Dewhirst, M.W.,
R.Z. Vinuya, E.T. Ong, B. Klitzman,
G. Rosner, T.W. Secomb, and J.F. Gross.
Effects of bradykinin (BK) on tumor and granulating normal tissue
capillary and venular hemodynamics. Rad. Res. 130:345-354, 1992.
PUBLICATIONS (cont.)
39. Fisher, A.J.,
N.W. Schrader, and B. Klitzman. Effects of chronic hypoxia on capillary flow
and hematocrit in rat skeletal muscle. Am. J. Physiol. 262:H1877-1883, 1992.
40. Wu, N.Z., B. Klitzman, R. Dodge, and M.W.
Dewhirst. Diminished
leukocyte-endothelium interaction in tumor microvessels. Cancer
Res. 52:4265-4268, 1992.
41. Dewhirst, M.W.,
Ong, E.T., Madwed, D., Klitzman, B.,
Secomb, T.W., Brizel, D., Bonaventura, J., Rosner, G., Kavanagh, B., Edwards,
J., and Gross, J. Effects of calcium
channel blocker flunarizine on the hemodynamics and oxygenation of tumor
microvasculature. Radiat. Res. 132:61-68,
1992.
42. Brizel, D.M., B. Klitzman, J.M. Cook, and M.W.
Dewhirst. A comparison of tumor and
normal tissue microvascular hematocrits and red cell fluxes in a rat window
chamber model. Int. J. Rad. Onc. Biol. Phys. 25:269-276, 1993.
43. Secomb, T.W.,
R. Hsu, M.W. Dewhirst, B. Klitzman,
and J.F. Gross. Analysis of oxygen
transport to tumor tissue by microvascular networks. Int J Rad Onc Biol Phys.
25:481-9, 1993.
44. Feldman, D.F.,
R.S. Sepka, and B. Klitzman. Tissue oxygenation and blood flow on
specialized and conventional hospital beds.
Ann. Plast. Surg., 30:441-444,
1993.
45. Vann, R.D.,
E.F. Ritter, M.D. Plunkett, C.W. Wyble, C.V. Bensen, W.J. Barwick, E.M. Mikat,
L.E. Palmos, W. Gerth, and B. Klitzman. Patency and blood flow in gas denucleated
arterial prostheses. J. Biomed. Mater. Res. 27:493-498, 1993.
46. Wigod, M.D. and
B. Klitzman. Quantification of in vitro endothelial cell
adhesion to vascular graft material. J. Biomed. Mater. Res. 27:1057-1062,
1993.
47. Wu, N.Z., B. Klitzman, and M.W. Dewhirst. Fluorescence videometric method for
quantifying capillary exchange. Microvasc. Res. 46:231-153, 1993.
48. Peterseim,
D.S., C.H. Meyers, D.M. Craig, J.S. Heinle, A.M. Jayawant, J.J. Devaney, B. Klitzman, and P. Van Trigt. Enhanced cardiac preservation with
oxygenated University of Wisconsin solution.
J. Surg. Res. 55:588-594,
1993.
49. Hoke, J.A.,
E.J. Burkes, J.T. White, M.B. Duffy, and B.
Klitzman. Blood flow mapping of
oral tissues. Int. J. Oral Maxil. Surg.
23:312-315, 1994.
50. Dewhirst, M.W.,
D. Madwed, R.E. Meyer, E.T. Ong, B.
Klitzman, G.L. Rosner, and R. Dodge.
Reduction in tumor blood flow in skin flap tumor after hydralazine is
not due to a vascular steal phenomenon.
Rad. Onc. Invest. 1:270-278, 1994.
PUBLICATIONS
(cont.)
51. Wu, N.Z., B.A.
Ross, C. Gulledge, B. Klitzman, R.
Dodge, and M.W. Dewhirst. Differences
in leucocyte-endothelium interactions between normal and adenocarcinoma bearing
tissues in response to radiation. Br. J. Cancer 69:883-889, 1994.
52. Klitzman, B. Rheology and the
regulation of oxygen transport. Microsurgery
15:369-373, 1994
53. Zhang, J., H.
Benveniste, B. Klitzman, and C.A.
Piantadosi. Effects of nitric oxide on
glutamate release during ischemia and reperfusion of rat brain. Stroke 26:345-354, 1995.
54. Kimura, H.,
N.Z. Wu, R. Dodge, D.P. Spencer, B.
Klitzman, T.M. McIntyre, and M.W. Dewhirst. Inhibition of radiation-induced up-regulation of leukocyte
adhesion to endothelial cells with the platelet-activating factor inhibitor,
BN52021. Int. J. Rad. Onc., Biol., Phys. 33:627-633, 1995.
55. Skarada, D.J.,
G. Erickson, K. Warnecke, T.V. du Laney, C. Greenberg, E.F. Ritter, and B. Klitzman. Assessment of thrombogenicity by three in vitro techniques. J. Biomed. Mater. Res. 29:1039-1045, 1995. (winner of Soc.
Biomaterials annual award)
56. Zhang, J., A.D.
Sam, B. Klitzman, and C.A.
Piantadosi. Inhibition of nitric oxide
synthase on brain oxygenation in anesthetized rats exposed to hyperbaric
oxygen. Undersea Hyperbaric Med
22:377-382, 1995.
57. Zavitsanos, G.,
L. Huang, W. Panza, D. Serafin, and B.
Klitzman. Maintenance of muscle
function following ischemia and reperfusion in rabbit forelimb. J.
Reconstr. Microsurg. 12:183-187, 1996.
58. Sonntag, K., J.
Hoke, B. Klitzman, and E.J.
Burkes. Pulpal response to cavity
preparation with the Er;YAG and Mark III free electron lasers. Oral
Surg. Oral Med. Oral Path.
81:695-702, 1996.
59. Sachse, R.E.,
S. Fink, and B. Klitzman. Pressure, blood flow, and transcutaneous
oxygen tension of the trochanter, sacrum and ischium in supine and lateral
positions. Surgical Forum, 1996.
60. Ritter, E.F.,
J.P. Anthony, L.S. Levin, C.P. Demas, B.
Klitzman, D. Skarada, and D. Serafin.
Microsurgical composite tissue transplantation at difficult recipient
sites facilitated by preliminary installation of vein grafts as arteriovenous loops. J.
Reconstr. Microsurg. 12:231-240,
1996.
61. Maynor, M.,
R.E. Moon, B. Klitzman, P.J.
Fracica, and A. Canada. Brown recluse
spider evenomation- a prospective trial of hyperbaric oxygen therapy. Acad.
Emerg. Med. 4:184-192, 1997.
62. Sharkawy, A.A.,
B. Klitzman, G.A. Truskey, and W.M.
Reichert. Engineering the tissue which
encapsulates subcutaneous implants: I. Diffusion properties. J.
Biomed. Mater. Res. 37:401-412,
1997.
PUBLICATIONS (cont.)
63. Ritter, E.F.,
M. Axelrod, K.W. Minn, E. Eades, A.M. Rudner, D. Serafin, and B. Klitzman. Modulation of ultraviolet light-induced damage: Beneficial
effects of tocopherol. Plast. Reconstr. Surg. 100:973-980,
1997.
64. Viscardi, P.,
E.A. Page, H.G. Clark, D. Serafin, and B.
Klitzman. Iloprost in alginate
decreases thrombogenicity of expanded poytetrafluoroethylene. J.
Reconstr. Microsurg. 13:303-306, 1997.
65. Ritter, E.F.,
Y.B. Kim, H. P. Reischl, D. Serafin, and B.
Klitzman. Heparin coating of vascular prostheses reduces
thromboemboli. Surgery 122:888-892, 1997.
66. Musselwhite,
J.M., B. Klitzman, W. Maixner, E.J.
Burkes. Laser Doppler flowmetry: A
clinical test of pulpal viability. Oral Surg. Oral Med. Oral Path. 84:411-419, 1997.
67. Sharkawy, A.A.,
B. Klitzman, G.A. Truskey, and W.M.
Reichert. Engineering the tissue which
encapsulates subcutaneous implants II: plasma-tissue exchange properties. J.
Biomed. Mater. Res. 40: 586-597, 1998.
68. Sharkawy, A.A.,
B. Klitzman, G.A. Truskey, and W.M.
Reichert. Engineering the
tissue which encapsulates subcutaneous implants III: overall transport
properties. J. Biomed. Mater. Res. 40:598-605, 1998.
69. Klitzman, B., C. Kalinowski, S.L.
Glasofer, and L. Rugani. Pressure
ulcers and pressure relief surfaces. Clin. Plast. Surg. 25:443-450, 1998.
70. Ritter, E.F.,
M.M. Fata, A.M. Rudner, and B. Klitzman. Heparin binding improves patency of long
microvascular prostheses. Plast. Reconstr. Surg. 101:142-6, 1998.
71. Mayberry,
A.J., Klitzman, B., Mathy, J.A.,
Levin, L.S., Philips, T.M., and Brown, S.A.
Cytokine levels at open fractures using microdialysis. Surg Forum 49:616-617, 1998.
72. Ritter, E.F., Cronan, J.C., Rudner, A.M., Serafin, D., Klitzman, B. Improved microsurgical
anastomotic patency with low molecular weight heparin. J. Reconstr. Microsurg. 14:331-336, 1998
73. Sachse,
R.E., Fink S.A., Klitzman B. Comparison of supine and lateral positioning
on various clinically used support surfaces.
Ann Plas Surg 41:513-518,
1998.
74. Sachse, R.E., Fink, S.A., and Klitzman,
B. Multimodality assessment of
specialty beds. Plast. Reconstr. Surg. 102:2381-2387, 1998
75. Bhat V.D., Klitzman B., Koger K.E., Truskey G.A.,
Reichert W.M. Improving endothelial
cell adhesion to vascular graft surfaces: Clinical need and strategies. J. Biomat.
Sci.-Polymer Ed 9:1117-1135, 1998
PUBLICATIONS (cont.)
76. Dewhirst, M.W., Ong E.T., Braun,
R.D., Smith B., Klitzman B., Evans
S.M., and Wilson D. Quantification of longitudinal tissue PO2
gradients in window chamber tumors: impact on tumor hypoxia. Br. J.
Cancer 79:1717-1722, 1999.
77. Ravin, A.G., Olbrich,
KC, Alexander, MA, Levin, LS, Klitzman,
B.
Modification of capsule formation around implants using
matrices. Surg Forum, 1999.
78. Sundin BM,
Hussein, M.A., Glasofer, S, El-Falaky, M.H., Abdel-Aleem, S.M., Sachse, R.E.,
and Klitzman, B. The role of allopurinol and deferoxamine in
prevention of pressure ulcers in pigs. Plast Reconstr Surg 104:1408-1421, 2000.
79. Brown SA,
Mayberry A, Mathy J, Phillips, TM, Klitzman B, Levin LS. The effect of
muscle flap transposition to the fracture site on TNF[alpha] levels in fracture
healing. Plast Reconstr Surg, 105:991-998, 2000.
80. Klitzman B., R.D. Braun, A.C.
Lockhart, L. Heller, M.W. Dewhirst, and H.I. Hurwitz. Wound-induced angiogenesis: A clinical model. Prog Appl Microcirc 24:11-15, 2000.
81. Dewhirst, MW, Klitzman B.,
Braun, R.D., Brizel, D.M., Haroon, Z.A., and Secomb, T.W. Review of methods to study oxygen transport
at the microcirculatory level. Int.
J. Cancer (Radiat. Oncol. Invest.)
90:237-255, 2000.
82. Moore, F.M., Klitzman,
B., Levin, L.S., and Brown, S.A.
Tumor necrosis factor-alpha levels in crushed rat muscle. Plast
Reconstr Surg, 2001.
83.
Ravin, AG, Olbrich, K.C., Levin, L.S., Usala, A.L., Klitzman, B. Long- and short-term effects of biological
hydrogels on capsule microvascular density around implants in rats. J. Biomed. Mater. Res. (Appl. Biomat.)
58:313-318, 2001.
84. Heller L, Levin LS, Klitzman B. Laser Doppler flowmeter monitoring of
free-tissue transfers: Blood flow in normal and complicated cases. Plast
Reconstr Surg 107:1739-1745, 2001.
85. Ettinger, S.N., Poellmann, C.P., Wisniewski,
N.A., Gaskin, A.A., Shoemaker, J.S., Poulson, J.M. Dewhirst, M.W., Klitzman, B. Urea as a recovery marker for quantitative
assessment of tumor interstitial solutes with microdialysis. Cancer Res. 61:7964-7970, 2001.
86. Wisniewski N, Klitzman B, Miller B, Reichert
WM. Decreased analyte transport through
implanted membranes: Differentiation of biofouling from tissue effects. J Biomed Mater Res 57: 513-521, 2001.
PUBLICATIONS (cont.)
87.
Wisniewski, N.A., Rajamand, N.,
Adamsson, U., Lins, P.E., Reichert, W.M., Klitzman, B.,
Ungerstedt, U. Analyte flux through
chronically implanted subcutaneous polyamide membranes differs in humans and
rats. Am J. Physiol: Endocrin Metab. 282:E1316-23, 2002.
88.
Stenken, J.A., Reichert, W.M., Klitzman, B. Magnetic resonance imaging of a tissue/implanted device
biointerface using in vivo microdialysis sampling. Anal Chem 74:4849-4854, 2002.
89. Lockhart, A.C., Braun, R.D., Yu, D., Ross,
J.R., Dewhirst, M.W., Humphrey, J.S., Klitzman, B., Yuan, F., Grichnik, J.M., Proia, A.D., Conway, D.A., Hurwitz,
H.I. A clinical model of dermal wound
angiogenesis. Wound Repair Regen. 11:306-13, 2003.
90. Lockhart, AC, Braun, R.D., Yu, D., Ross, J.R., Dewhirst, M.W., Humphrey, J.S.,
Thompson, KM, Klitzman, B., Yuan, F., Grichnik, J.M., Proia, A.D.,
Conway, D.A., Hurwitz, H.I Reduction
of wound angiogenesis in patients treated with BMS-275291, a broad spectrum
matrix metalloproteinase inhibitor. Clin
Can Res, 9:586-593, 2003.
91. Erdmann D, Sweis R, Wong MS, Eyler CE,
Olbrich KC, Levin LS, Germann G, Klitzman B. Current perspectives of
orthogonal polarization spectral imaging in plastic surgery. Chirurg. 73:827-32, 2002.
92. Erdmann D, Sweis
R, Wong MS, Niklason LE, du Laney TV, Levin LS, Klitzman B, Olbrich
KC. Vascular endothelial growth factor
expression in pig latissimus dorsi myocutaneous flaps after ischemia
reperfusion injury. Plastic Reconstr Surg 111:775-80, 2003.
93.
Erdmann D, Sweis R, Heitmann C, Yasui K, Olbrich KC, Levin LS, Sharkawy AA, Klitzman
B. Side-to-side sutureless
vascular anastomosis using magnets. J Vasc Surg 40:505-511, 2004.
94.
Wong, M.S., Erdmann, D., Sweis, R.,
Pollmann, C., Farrar, M., Georgiade, G.S., Levin, L.S., Olbrich, K.C., Klitzman,
B. Basic fibroblast growth factor expression following
surgical delay of rat transverse rectus abdominis myocutaneous flaps.
Plastic Reconstr Surg 113:2030-2036,
2004.
95.
Dai QS, Huang JH, Klitzman B, Dong CM, Goldschmidt-Clermont PJ, March
KL, Rokovich J, Johnstone B, Rebar EJ, Spratt SK, Case CC, Kontos CD, Annex
BH. Engineered zinc finger-activating
vascular endothelial growth factor transcription factor plasmid DNA induces
therapeutic angiogenesis in rabbits with hindlimb ischemia. Circ 110: 2467-2475, 2004.
96. Erdmann D,
Pippen AM, Moquin KJ, Sweis R, Niklason LE, Levin LS, Olbrich KC, Klitzman B. Immunohistochemical identification of
vascular endothelial growth factor in pig latissimus dorsi musculocutaneous
flaps following ischemia-reperfusion injury .
Ann Plast Surg 53:398-403, 2004.
PUBLICATIONS (cont.)
97.
Heitmann, C., Khan, F.N., Olbrich, K.C., Sharkawy, A.A., and Klitzman, B. Sutureless anastomosis of a vein graft using
magnets. Plast Reconstr Surg, submitted, 2004.
98.
Poellmann, C.P., Ettinger, S.N., Wisniewski,
N.A., Poulson, J.M. Dewhirst, M.W., Klitzman, B. Effects
of moderate hyperglycemia on tumor microdialysate metabolites. Int J
Rad Onc Biol Phys., in press, 2005.
99. Chan BP, Liu
WG, Klitzman B, Reichert WM, and Truskey GA. In vivo performance of dual ligand augmented endothelialized
expanded polytetrafluoroethylene vascular grafts J Biomed Mater Res. B: Appl Biomat
72B: 52-63, 2005
103. Olbrich KC,
Meade R, Bruno W, Heller L, Klitzman
B, Levin LS. Halofuginone inhibits collagen
deposition in fibrous capsules around implants. Ann Plast Surg 54:293-6, 2005
ABSTRACTS
1. Klitzman, B. and B.R. Duling.
Effects of oxygen and norepinephrine on capillary blood flow in contracting
muscle. Fed. Proc. 36:451, 1977.
2. Klitzman, B. and B.R. Duling.
Arteriolar diameter and capillary density in muscle: Independent or
reciprocal variables. The Physiologist 20:51, 1977.
3. Klitzman, B. and B.R. Duling.
Acute hematocrit changes in capillaries of striated muscle during functional
hyperemia.
Microvasc. Res. 15:267, 1978.
4. Klitzman, B. and B.R. Duling.
Causes of low microvascular hematocrit in hamster cremaster capillaries.
Microvasc. Res. 17:S70, 1979.
5. Klitzman, B. and P.C. Johnson.
Alteration of red blood cell distribution in striated muscle capillaries.
NATO:ASI on Biorheology, Houston, TX, 1980.
6. Klitzman, B. and P.C. Johnson.
Heterogeneity of red cell flux and capillary hematocrit in striated muscle
capillaries. Microvasc. Res. 20:116, 1980.
7. Klitzman, B., and P.C. Johnson. Factors
affecting the distribution of red blood cells at capillary bifurcations. Microvasc. Res. 21:247‑248, 1981.
8. Klitzman, B. Capillary hematocrit
and its relation to oxygen transport. 34th Annual Conference on
Engineering in Medicine and Biology. Houston, TX, Sept., 1981.
9. Klitzman, B., A.S. Popel, and B.R.
Duling. Experimental and theoretical studies of oxygen transport in
superfused hamster cremaster muscle. Microvasc. Res. 23:261‑262,
1982.
10. Klitzman, B., J. Myers, R.P. Watts, and
P.C. Johnson. Measurement of microvascular hematocrit and red cell
velocity using stroboscopic epifluorescence microscopy.
Fed. Proc. 41:1759, 1982.
11. Popel,
A. S., B. Klitzman, and B.R.
Duling. Theoretical analysis of oxygen transport in exposed skeletal
muscle. Int. J. Microcirc.
1(3):311, 1982.
12. Klitzman, B. Effect of
fluorescent labeling of red cells on flow through capillaries.
Microvasc. Res. 25:241‑242, 1983.
13. Klitzman, B. Mitochondrial
distribution in hamster cremaster muscle. Physiologist 26:A93, 1984.
14. Klitzman, B. Evidence for
decreased deformability of fluorescent labeled red cells.
Proc. Int. Un. Physiol. Sci. Cong., Sydney, 15:200,
1983.
ABSTRACTS (cont.)
15. Fleming,
B. P., B. Klitzman, and W.O.
Johnson. A periodic differential detector for microvascular
velocimetry. Microvasc. Res. 27:243, 1984.
16. Klitzman, B. Relative velocity of
red cells and sub‑micron particles in hamster cremaster capillaries. Int. J. Microcirculation 3:386, 1984.
17. Fleming,
B. P., B. Klitzman, and W.O.
Johnson. Erythrocyte velocimetry using a periodic differential detector. Int. J. Microcirculation 3:540,
1984.
18. Klitzman, B. Relative increase in
capillary hematocrit following isovolemic hemodilution.
Microvasc. Res. 29:231, 1985.
19. Klitzman, B., R.S. Sepka, and D.
Serafin. Effects of isovolemic
hemodilution on rat skin flap survival. Proc. Intl. Biorheol. Conf., 1986.
20. Jenkins, S., J.
Gelman, R. Sepka., D. Serafin, and B.
Klitzman. Reduction of skin flap
necrosis with difluoromethylornithine (DFMO) and norepinephrine depletion. Am. Assoc. Hand. Surg., 1986.
21. Gelman, J., S.
Jenkins, J. Bartolome, K. Oothout, D. Serafin,
S. Schanberg, and B. Klitzman. Increased survival of rat skin flaps with
difluoromethylornithine (DFMO). Am.
Soc. Plast. Reconstr. Surg., Los Angeles, 1986
22. Klitzman, B., J. Gelman, S. Jenkins, L.
Huang, and D. Serafin. Determinants of
skin flap survival: Substrate delivery, substrate demand, and cell destruction. Int. Soc. Microsurg., Italy, 1986
23. Bowman, K.F.,
J.E. Riviere, N.A. Monteiro, S.W. Crane, D. Serafin, and B. Klitzman. Preliminary
studies on the in vitro isolated perfused porcine skin flap for physiological
modeling in surgical research. Am. Col.
Vet. Surg., San Antonio, 1987
24. Panza, W., L.
Huang, D. Serafin, and B. Klitzman. Ischemia-reperfusion effects on skeletal
muscle function. Plast. Surg. Res.
Counc., Boston, 1987
25. Chang, S.C., D.
Serafin, and B. Klitzman. Ultrasonic thrombus generation in the
microvasculature. Plast. Surg. Res.
Counc., Boston, 1987.
26. Barber, W.B.,
J. Bartolome, D. Serafin, and B.
Klitzman. Pharmacologic modulation
of cutaneous ornithine decarboxylase activity using
difluoromethylornithine. Plast. Surg.
Res. Counc., Boston, 1987.
27. Klitzman, B., N. Schrader, R. Sepka,
and D. Serafin. Relative effects of red
cells and platelets on rat skin flap survival.
Fed. Proc. 46:1531, 1987.
ABSTRACTS (cont.)
28. Klitzman, B., J. Gelman, D. Serafin, S.
Schanberg, and J. Bartolome. Protection
of rat skin against ischemic damage with difluoromethylornithine. Fed. Proc. 46:1120, 1987.
29. Klitzman, B., K. Oothout, R. Sepka, and
D. Serafin. Effects of prostanoids on
rat skin flap survival. Fourth World
Congress for Microcirculation, 1987.
30. Klitzman, B., S.D. Jenkins, R. Sepka,
W. Barwick, and D. Serafin. Invasive
and non-invasive use of laser Doppler flowmeter to monitor free tissue
transfers. Fourth World Congress for
Microcirculation, 1987.
31. Huang, L., W.
Panza, D. Serafin, and B. Klitzman. Ischemia- reperfusion effects on skeletal
muscle function. Am. Soc. Reconstr.
Microsurg., 1987.
32. Jenkins, SD,
R.S. Sepka, C.P. Demas, D. Serafin, and B.
Klitzman. Non-invasive and invasive
clinical use of laser Doppler flowmetry for assessment of perfusion in free
tissue transfers. Am. Soc. Reconstr.
Microsurg., 1987.
33. Chang, S.C., D.
Serafin, and B. Klitzman. Ultrasonic thrombus generation in the
microvasculature. Am. Assoc. Hand Surg.,
1987.
34. Goldberg, M.,
D. Serafin, and B. Klitzman. Quantification of neutrophil activation
following ischemia/reperfusion of hamster cremaster muscle. Am. Assoc. Hand Surg., 1987
35. Demas, C.P.,
E.F. Ritter, R.D. Vann, R.S. Sepka, R.W. Burk, W.J. Barwick, and B. Klitzman. Improved biocompatibility of synthetic microvascular
prostheses. Plast. Surg. Chief Res.
Conf., 1988.
36. Burk, R.W., D.
Serafin, and B. Klitzman. Toxic effects of catecholamines in
skin. Am. Soc. Aesth. Plast. Surg.,
1988.
37. Ritter, E.F.,
B.G. Forley. Stimulation of epidermal proliferation by polyamines in human
facial skin grafted to the athymic nude mouse.
Am. Soc. Aesth. Plast. Surg., 1988.
38. Forley, B.G.,
L. Huang, D. Serafin, J.V. Bartolome, and B.
Klitzman. The potential role of
polyamine inhibition in keloid therapy.
Plast. Surg. Res. Council, San Francisco, CA, 1988.
39. Eshbaugh, WG,
BG Forley, EF Ritter, D Serafin, and B
Klitzman. Polyamines and UV-B
radiation stimulate DNA synthesis in human epidermis. Plast. Surg. Res.
Council, 1988.
40. Eshbaugh, W.G.,
B.G. Forley, E.F. Ritter, D. Serafin, and B.
Klitzman. Stimulation of epidermal
DNA synthesis by UV-B radiation and its inhibition by
difluoromethylornithine. Am. Soc.
Plast. Reconstr. Surg., Toronto, 1988.
[awarded First Prize in the Investigator category of the PSEF Essay
Contest]
ABSTRACTS (cont.)
41. Klitzman, B., N. Schrader, and P.
Elizalde. Increases in perfused
capillary density, capillary hematocrit and systemic hematocrit induced by
chronic exposure to hypoxia and cold.
FASEB J. 2:A1870, 1988.
42. Perona, B.P.,
M. Clinton, and B. Klitzman. In vivo platelet aggregation in microvessels
following ultrasonic stimulation. FASEB J.
2:A1876, 1988.
43. Ritter, E.F.,
R.D. Vann, R.S. Sepka, and B. Klitzman. Reduction in thrombogenicity of
microvascular prostheses. FASEB J. 2:A1877, 1988.
44. Pederson, WC,
J. Goldberg, R Sepka, M Clinton, and B
Klitzman. Improved salvage rate of
transplanted tissues with laser Doppler monitoring. Am. Soc. Reconstr. Microsurg., 1988.
45. Goldberg, J.,
R.S. Sepka, W.C. Pederson, M. Clinton, W.J. Barwick, and B. Klitzman. Mapping of
laser Doppler flow on common cutaneous donor sites for reconstructive
surgery. Am. Soc. Reconstr. Microsurg.,
1988.
46. Ritter, E.F.,
R.D. Vann, R.S. Sepka, and B. Klitzman. Reduction in thrombogenicity of
microvascular prostheses. Am. Assoc.
Hand Surg., 1988.
47. Perona, B.P.,
J.V. Bartolome, R.S.Sepka, D. Serafin. and B.
Klitzman. Protection of rat skin
flaps with acute difluoromethylornithine.
FASEB J. 3:A1398, 1989.
48. Koger, K., C.V.
Bensen, R.D. Vann, H.G. Clark, and B.
Klitzman. Decreased thrombogenicity
of biomaterials with chitosan. FASEB J.
3:A1391, 1989.
49. Clinton, M.,
R.S. Sepka, D. Bristol, W.J. Barwick, W.C. Pederson, D. Serafin, and B. Klitzman. Establishment of flow ranges for uncomplicated autologous tissue
transplants. SE Soc. Plast. Reconstr.
Surg, 1989.
50. Clinton, M.,
R.S. Sepka, D. Bristol, W.J. Barwick, W.C. Pederson, D. Serafin, and B. Klitzman. Normal laser Doppler flow ranges for autologous tissue
transplants. Sr. Plast. Surg. Res.
Conf., 1989.
51. Minn, K.W., D.
Serafin, and B. Klitzman. Venous reconstruction of rat femoral vein
using composite polyurethane microvascular prostheses. Am. Soc. Plast. Reconstr. Surg, 1989.
52. Clinton, M.,
R.S. Sepka, D. Bristol, W.J. Barwick, W.C. Pederson, D. Serafin, and B. Klitzman. Establishment of flow ranges for uncomplicated autologous tissue
transplants. Am. Soc. Plast. Reconstr.
Surg, 1989.
53. Cronan, J.C.,
W.J. Barwick, D. Serafin, and B.
Klitzman. Improved skin flap
survival using a low molecular weight fraction of heparin. Am. Soc. Surg. Hand, 1989.
ABSTRACTS (cont.)
54. Minn, K.W., D.
Serafin, and B. Klitzman. Successful prosthetic reconstruction of rat
femoral veins. Am. Assoc. Hand Surg.,
1989.
55. Young, K.B.,
P.J. Fracica, B. Klitzman, E.
Camporesi, and W.D. Watkins. Pulmonary
oxygen toxicity can be reduced by gradual hyperoxia. Chest 96:155S, 1989.
56. Page, E., H.G.
Clark, D. Serafin, and B. Klitzman. Decreased thrombogenicity of biomaterials
with Iloprost. FASEB J. 4:A1265, 1990.
57. Bensen, C.V.,
K. Koger, R.D. Vann, B. Klitzman. Quantification of denucleation of vascular
prostheses and effects on thrombogenicity.
FASEB J. 4:A1260, 1990.
58. Minn, K.W., D.
Serafin, and B. Klitzman. Microvenous reconstruction of rat femoral
veins with composite polyurethane prostheses.
FASEB J. 4:A1266, 1990
59. Sepka, R.S., D.
Serafin, W.C. Pederson, W.J. Barwick, and B.
Klitzman. Effects of autologous
transplantation on cutaneous perfusion.
FASEB J. 4:A1270, 1990.
60. Axelrod, M.S.,
K.W. Minn, E. Eades, D. Serafin, and B.
Klitzman. Tocopherol decreases UV
induced epidermal damage. FASEB J. 4:A1139, 1990.
61. Page, E., H.G.
Clark, D. Serafin, and B. Klitzman. Effect of alginate and prostacyclin analog
on thrombogenicity of ePTFE. Trans.
Soc. Biomater. 16:27, 1990.
62. Koger, K.E., D.
Serafin, and B. Klitzman. Reduced thrombus adhesion to expanded
polytetrafluoroethylene using chitosan.
FASEB J. 4:A1264, 1990.
63. Bensen, C.V.,
R.D. Vann, B. Klitzman. Quantification of gas denucleation and
thrombogenicity of vascular grafts.
Trans. Soc. Biomater. 16:98, 1990.
64. Minn, K.W., D.
Serafin, and B. Klitzman. Reconstruction of rat femoral veins with
microvenous prostheses. Trans. Soc.
Biomater. 16:282, 1990.
65. Koger, K.E., D.
Serafin, and B. Klitzman. Chitosan decreases thrombus adhesion to
expanded polytetrafluoroethylene.
Plastic Surg. Research Council, 1990.
66. Cuffe, M., E.L.
Page, R.S. Sepka, W.C. Brown, B.
Klitzman. Quantification of normal
cutaneous blood flow in hands and feet by laser Doppler flowmetry. Am. Soc. Reconstr. Microsurg., 1990.
67. Klitzman, B., N.W. Schrader. Mitochondrial volume density is a
physiological variable. The
Physiologist, 1990.
ABSTRACTS (cont.)
68. Fata, M.M., D.
Serafin, B. Klitzman. Heparin binding improves the patency of
ePTFE microvascular grafts. Plast.
Surg. Res. Council, 1991.
69. Fata, M.M., D.
Serafin, B. Klitzman. High patency of clinically useful lengths of
ePTFE microvascular grafts using heparin binding. S.E. Soc. Plast. Reconstr. Surg., 1991.
70. Brizel, D.M.,
M.W. Dewhirst, J.M. Cook, B. Klitzman. Microvascular tumor and normal tissue
hematocrits and red cell flux in a rat window chamber model. 9th Int. Cong. Rad. Res., 1991.
71. Ong, E.T., M.W.
Dewhirst, D. Madwed, B. Klitzman. Effects of flunarizine on oxygenation of
mammary adenocarcinoma. 9th Int. Cong.
Rad. Res., 1991.
72. Fata, M., D.
Serafin, B. Klitzman. Heparin coating maintains patency of
clinically useful microvascular prostheses. Proc. 5th World Cong. Microcirc.
25, 1991.
73. Kim, Y.B., D.
Serafin, B. Klitzman. Quantification of arteriolar microemboli
downstream from microvascular prostheses.
Proc. 5th World Cong. Microcirc. 51, 1991.
74. Fisher, A.J.
and B. Klitzman. Effects of chronic hypoxia on capillary
hematocrit and blood flow in rat skeletal muscle. Proc. 5th World Cong. Microcirc., 1991.
75. Nickel, B.A., B. Klitzman. Effects of chronic hypoxia on pial microcirculation. Proc. 5th World Cong. Microcirc. 79, 1991.
76. Klitzman, B. Future interface between microvascular surgery and
microcirculation. Proc. 5th World Cong.
Microcirc. 51, 1991.
77. Brizel, D.M.,
M.W. Dewhirst, J.M. Cook, and B.
Klitzman. Microvascular tumor and
normal tissue hematocrits and red cell flux in a rat window chamber model. Proc. 5th World Cong. Microcirc. 11, 1991.
78. Dewhirst, M.W.,
D. Madwed, E.T. Ong, and B. Klitzman. Effects of flunarizine on the
microcirculation of mammary adenocarcinoma.
Proc. 5th World Cong. Microcirc.
20, 1991.
79. Secomb, T.W.,
R. Hsu, M.W. Dewhirst, B. Klitzman,
and J.F. Gross. Simulation of oxygen
transport to tumor tissue by microvascular networks. FASEB J. 6: , 1992.
80. Li, Z., D.
Serafin and B. Klitzman. Arteriolar hemodynamics downstream from
implanted microvascular prostheses.
Plast. Surg. Res. Council, 1992.
81. Li, Z., D.
Serafin, and B. Klitzman. Measurement of arteriolar blood flow
downstream from microvascular prostheses.
Am. Soc. Reconstr. Microsurg., 1992.
ABSTRACTS (cont.)
82. Peterseim,
D.S., C.H. Meyers, D.M. Craig, J.S. Heinle, A.M. Jayawant, J.J. Devaney, B.M. Klitzman, and P. Van Trigt. Enhanced cardiac preservation with
oxygenated University of Wisconsin solution.
Am. Assoc. Acad. Surg., 1992.
83. Wigod, M.D. and
B. Klitzman. Quantification of in
vitro endothelial cell adhesion to vascular graft material. Soc. Biomater., 1993.
84. Sonny, M., S.D.
Sam, C.A. Piantadosi, and B. Klitzman. Effects of hyperbaric oxygen on arterioles
of the cremaster muscle. FASEB J.,
1993.
85. Sam, S.D., M.
Sonny, C.A. Piantadosi, and B. Klitzman. Effects of hyperbaric oxygen on muscle oxygen
tension. FASEB J., 1993.
86. Scher D.M., R.
Sachse, A. Canada, and B. Klitzman.
The effects of hyperbaric oxygen on reperfusion injury in skeletal muscle. Plast. Surg. Res. Council, 1993.
87. Maynor, M.,
R.E. Moon, B. Klitzman, P.J.
Fracica, and C.R. Geren. HBO and the
effect of brown recluse spider venom in rabbits. Undersea Hyperbar. Med. Soc., 1993.
88. Sonny, M., S.D.
Sam, C.A. Piantadosi, and B. Klitzman. Effects of hyperbaric oxygen on arterioles
of the cremaster muscle. Undersea Hyperbar.
Med. Soc., 1993.
89. Sam, S.D., M.
Sonny, C.A. Piantadosi, and B. Klitzman. Effects of hyperbaric oxygen on muscle
oxygen tension. Undersea Hyperbar. Med.
Soc., 1993.
90. Scher D.M., R.
Sachse, A. Canada, and B. Klitzman.
Hyperbaric oxygen effects reperfusion injury in rat skeletal muscle. Undersea Hyperbar. Med. Soc., 1993.
91. Klitzman B., N.W. Schrader, R.E.
McLendon, and M.W. Dewhirst.
Quantitative morphology of rat carcinoma with relevance to
oxygenation. FASEB J , 1994.
92. Zhang, J., A.D.
Sam, B. Klitzman, and C.A.
Piantadosi. Inhibition of nitric oxide
synthase does not decrease cerebral blood flow or brain oxygen tension in rats
exposed to hyperbaric oxygen. Undersea
Hyperbar. Med. Soc., 1994.
93. Sachse, R., R.
Sepka, D. Feldman, D. Serafin, and B.
Klitzman. Effects of polarized
light on healing of skin graft donor sites.
Plast. Surg. Res. Council, 1994.
94. Skarada, D.J.,
K.L. Warnecke, G.A. Erickson, T.V. du Laney, C. Greenberg, E.F. Ritter, and B. Klitzman. In vitro assessment of thrombogenicity of vascular graft
material. Soc. Biomat., 1995.
ABSTRACTS (cont.)
95. Hussein, M., B. Klitzman, C.Y. Pang, D.
Serafin. A clinicaly relevant model for
chronic pressure-induced injury. Trans. Am Soc. Reconstr. Microcurg., 10:161,
1995.
96. Steele, T.M.,
D.J. Skarada, J. Parker, D.R. Arnelle, C.S. Greenberg, J.D. Folts, J.S.
Stamler, and B. Klitzman. Nitrosylated albumin: a novel antithrombotic
coating for vascular grafts. Plast.
Surg. Res. Council. 1995.
97. Hussein M,
Abdelaleem S, Elfalaky M, Serafin D, Klitzman B. Correlation between skeletal-muscle high-energy
adenine-nucleotide content and applied pressure. FASEB J 9: A693-4, 1995.
98. duLaney, T.V.,
G. Truskey, and B. Klitzman. Endothelial cell adhesion to expanded
polytetrafluoroethylene following fibronectin coating. 5th World Biomaterials Congress 1:560, 1996.
99. Skarada, D.J.,
T. Steele, E.F. Ritter, and B. Klitzman. Continual in vivo assessment of vascular prostheses. Trans. 5th World Biomaterials Congress
1:278, 1996.
100. Sharkawy,
A.A., B. Klitzman, G.A. Truskey, and
W. M. Reichert. Diffusion properties of
capsular tissue. Trans. 5th World
Biomaterials Congress 2:132, 1996.
101. Galdino, G.,
D. Serafin, and B. Klitzman. A chronically hypoxic and ischemic rat
dorsal skin flap: a novel model for wound healing studies. Plast. Surg. Res. Council, 1996.
102. Levin, L.S.,
E. Marincea, D. Spencer, M.W. Dewhirst, and B. Klitzman. Reversal of
radiation injury to bone using hyperbaric oxygen therapy. Plast. Surg. Res. Council, 1996.
103. Sachse, R.E.,
S.A. Fink, B. Klitzman. Assessment of pressure, blood flow, and
oxygenation in weight-bearing and non-weight-bearing skin on various support
surfaces. 6th World Congress for
Microcirculation, 1996.
104. Klitzman, B., T.M. Chen, M.M.Fata, M.W.
Dewhirst. Blood flow and perfused
capillary density in oral tissues following irradiation. 6th World Congress for Microcirculation,
1996.
105. Sachse, R.E.,
S. Fink, and B. Klitzman. Pressure, blood flow, and transcutaneous
oxygen tension of the trochanter, sacrum and ischium in supine and lateral
positions. Surgical Forum, 1996
106. du Laney,
T.V., G.A. Truskey, and B. Klitzman. Flow chamber determination of platelet
aggregation on ePTFE following transplant of microvascular endothelial
cells. Tissue Engineering Society (charter meeting), 1996.
107. Lin, C.H.,
L.S. Levin, F.C. Wei, and B. Klitzman.
Effects of denervation on capillary blood flow in rat cremaster
muscle. Plast. Surg. Res. Council, 1997.
ABSTRACTS (cont.)
108. Sharkawy,
A.A., B. Klitzman, G.A. Truskey, and
W. M. Reichert. Using surface porosity
to increase the vascularity of tissue encapsulating long term subcutaneous
implants. Microcirculation, 1997.
109. Sharkawy,
A.A., B. Klitzman, G.A. Truskey, and
W. M. Reichert. Enhancing transport
through encapsulant tissue. Am. Chem. Soc., 1997.
110. du Laney,
T.V., B. R. Buckley, S.N. Mason, A.R. Whorton, K.S. Guice, and B. Klitzman. Human microvascular endothelial cells for transplantation: Assessment of nitric oxide synthase. Microcirculation, 1997.
111. Wisniewski,
N., B. Klitzman, and W.M.
Reichert. In vitro demonstration of
biofouling and mass transfer effects on implanted biosensor membranes. Trans.
Soc. Biomater., 1998.
112. Koger, K.E.,
L.S. Levin, and B. Klitzman. Effects of internal pressure on perfusion of
skin. FASEB J, 1998.
113. Koger, K.E., B. Klitzman., and L. S. Levin. Balloon dissection accelerates tissue expansion
and increases flap advancement. Plast Surg Res Council, 1998.
114. Rhie, J.W., B. Klitzman., M. McArdle, L.S. Levin,
and S.A. Brown. Preadipocyte viability
in a biomatrix: Model for soft tissue augmentation. Plast Surg Res Council, 1998.
115. Mathy, J.S.,
A.J. Mayberry, B. Klitzman., T.
Phillips, R. Gruninger, L. S. Levin, and S.A. Brown. Assessment of cytokines in contaminated open fractures with
microdialysis. Musculo-skeletal Infection Society, 1998. Winner of Best Paper Award
116. Koger, K.E., B. Klitzman., and L. S. Levin. Enhancement of tissue expansion using
balloon dissection. Plast Surg Sr. Resident’s Conf., 1998.
117. Koger, K.E., B. Klitzman., and L. S. Levin.
Acceleration of tissue expansion using balloon dissection. Southeastern
Soc. Plast. Reconstr. Surg., 1998.
First Place, Resident’s Competition.
118. A.J. Mayberry,
A.J., J.S. Mathy, B. Klitzman., T.
Phillips, R. Gruninger, L. S. Levin, and S.A. Brown. Cytokine levels in open fractures using microdialysis. Am.
Col. Surg.: Scientific Conference, 1998.
119. Heller, L., LS Levin, and B. Klitzman. Pearls and Pitfalls of laser Doppler flowmeter monitoring of free
tissue transfers. Am. Soc. Reconstr. Microsurg., 1999.
120. Klitzman, B. Microsurgical Training. Invited
Lecture, Am. Soc. Reconstr. Microsurg.,
1999.
ABSTRACTS (cont.)
121. Moore,
F.M., Levin, L.S., Klitzman, B., and
Brown, S.A. A new wound model for the
study of acute soft tissue injury using microdialysis. FASEB
J 25:, 1999.
122. Schuetz, TC, Ravin, AR, Brown SA, Levin, LS,
and Klitzman, B. Cell seeding
enhances functional vascular density surrounding chronic implants. Plast.
Surg. Res. Council, 1999.
123. Moore, F.M., Klitzman, B., Levin, L.S., and Brown, S.A. Tumor necrosis factor-alpha levels in
crushed rat muscle. Plast. Surg. Res. Council, 1999.
124. Brown, S.A., Mathy, J.A., Mayberry, A.J., Klitzman, B., and Levin, L.S. Time course of cytokine production in canine
open fractures. Plast. Surg. Res. Council, 1999.
125. Olbrich, KC, Ravin, A, Usala, A, Alexander, M, Levin,
LS, Klitzman, B. Capsule formation around chronic implants
modified by various matrices. NC Tissue Engin Interest Group, 1999.
126. Brown SA,
Phillips, T, Mayberry A, Mathy J, Klitzman B, Levin, LS. The effect of
Staphylococcus aureus on TNFa and IFNg on bone healing. Experimental Biology, 1999
127.
Brown SA, Mayberry A, Phillips T, Klitzman
B, Levin LS. The effect of a surgical flap on TNFa and IFNg levels in bone healing. Muscloskeletal Infection Society, 1999.
128. Brown SA, Mayberry A, Phillips T, Klitzman
B, Levin LS. Interleukin-8 levels are influenced by staphylococcus aureus. Muscloskeletal
Infection Society, 1999.
129. Kramer N, Brown SA, Smeds KA, Grinstaff MW, Levin LS, and Klitzman
B. Transplantation of preadipocytes in
methacrylate modified hyaluronic acid. Plast.
Surg. Res. Council, p. 43B, 2000.
130. Poellmann CP, Ettinger
SN, Levin LS, Dewhirst MW, and Klitzman
B. Biological signaling in tumor interstitium using
microdialysis. Plast. Surg. Res. Council, p. 27B, 2000.
131. Heller L, Levin LS, Brizel DM, and Klitzman B. Orthogonal polarization spectral imaging: A
revolutionary clinical tool for intravital microscopy.
Plast. Surg. Res. Council, p.
26A, 2000.
132. Gelaw B, Levin LS, Saito W, Chen Y,
Hurwitz H, Dewhirst MW, and Klitzman B. Wound-induced angiogenesis and its
pharmacologic inhibition. Plast. Surg. Res. Council, p. 44A, 2000.
133. Kolb A, Swank GM, Brown SA, Klitzman B, and Levin LS. Influence of muscle flaps on bone IL-8 mRNA
levels in canine open fractures. Plast.
Surg. Res. Council p. 2A, 2000.
134. Mastorakos DM, Shea CR, ElHadidy M, Levin LS, and Klitzman B. Effect of CO2 laser resurfacing
in random pattern skin flaps in swine. Plast.
Surg. Res. Council, p. 24B, 2000.
ABSTRACTS (cont.)
135. Klitzman, B and Olbrich KC. Orthogonal polarization spectral imaging: A
new tool for chronic intravital microscopy. NC Tissue Engin Interest Group, 2000.
136. Lockhart CA,
Braun RD, Dewhirst MW, Humphrey JS, Yuan F, Grichnik J, Proia A, Conway D, Klitzman
B, and Hurwitz HI. Wound
angiogenesis inhibition as a marker for anti-angiogenic efficacy. FASEB J 14:A35, 2000.
137. Brown SA,
Philips TM, Mathy J, Klitzman B, and Levin LS. IL-8 levels in infected bone marrow are modulated by a muscle
flap. FASEB J 14:A177, 2000.
138. Brown SA,
Philips TM, Mathy J, Klitzman B, and Levin LS. IL-8 levels in infected bone marrow are modulated by a muscle
flap. FASEB J 14:A177, 2000.
139. Olbrich KC, Ravin AG, Usala A-L, Levin LS, and Klitzman B. Vascular density and capsule thickness
around implanted devices. FASEB J 14:A445, 2000.
140. Ettinger
SN, Poellmann CC, Poulson JM, Dewhirst MW, and Klitzman B. A novel recovery marker to validate tumor
microenvironment with microdialysis. 2nd
International Symposium on Microdialysis in Drug Research and Development.
2000.
141.
Poellmann CC, Ettinger SN, Wisniewski NA, Brown SA, Dewhirst MW, and Klitzman
B. Tumor metabolites during hyperglycemia. 2nd International Symposium on
Microdialysis in Drug Research and Development. 2000.
142.
Poellmann CC, Ettinger SN, Wisniewski NA, Dewhirst MW, and Klitzman B. Analysis of tumor glucose concentrations
prior to and during hyperglycemia. 11th
International Conference on Chemical Modifiers of Cancer Treatment. 2000.
143. Sweis R.N., Olbrich, K.C., Levin, L.S., and Klitzman, B. Chronic
percutaneous intravital microscopy using orthogonal polarization spectral
imaging. Plast. Surg. Res. Council, 2001.
144.
Erdmann, DE, Sweis, RN, Wong, MW, Olbrich, KC, Levin, LS, and Klitzman, B. Ischemia and reperfusion in pig latissimus
dorsi myocutaneous flaps. Plast. Surg. Res. Council, 2001.
144.
Klitzman, B, Sweis R.N., Olbrich, K.C.
Chronic intravital microscopy using orthogonal polarization spectral
imaging. FASEB J, 2001.
145. Robles, RA, N.C. Kramer, Brown, S.A., Levin, L.S., Klitzman, B. Pre-coating of breast implants with autologous fat
cells to reduce the foreign body reaction.
Am. Soc. Aesth. Plast. Surg., 2001.
ABSTRACTS
(cont.)
146. Sweis R.N., Olbrich, K.C., Levin, L.S., and Klitzman,
B.
Chronic percutaneous intravital microscopy in nude mice using
orthogonal polarization spectral imaging.
POS-2-9, 7th World Cong.
Microcirc., 2001.
150. Yasui, K., B. Klitzman, JS Stamler,
LS Levin, and MR Zenn. Vasodilator of
O-nitrosoethanol versus lidocaine in microvascular surgery. Plast. Surg. Res. Council, 2002.
151. Klitzman, B., D Erdmann, R
Sweis, V McClory, KC Olbrich, and AA Sharkawy.
Vascular anastomoses with magnets: An attractive idea. Plast. Surg. Res. Council, 2002.
152. Wong,
MS, D Erdmann, R Sweis, KC Olbrich, and B Klitzman. Comparison of viability and basic-fibroblast
growth factor (b-FGF) expression following surgical delay of rat transverse
rectus myocutaneous (TRAM) flaps. Plast.
Surg. Res. Council, 2002.
153. Erdmann, D, R
Sweis, AM Pippen, KJ Moquin, MS Wong, LE Niklasson, LS Levin, KC Olbrich, and B. Klitzman. Quantitative
and immunohistochemical expression of vascular endothelial growth factor (VEGF)
in pig latissimus dorsi myocutaneous flaps. Am Soc. Plast.
Surg, 2002.
154. Klitzman, B., D Erdmann, R Sweis, V
McClory, KC Olbrich, and AA Sharkawy.
Vascular anastomoses using magnets: An attractive idea. Plast.
Surg. Res. Council, 2002.
155. Klitzman, B., D Erdmann, R Sweis, V
McClory, KC Olbrich, and AA Sharkawy.
Efficacy of a magnetic vascular anastomotic device. Am
Soc. Plast. Surg, 2002.
156. Dai, Q. , J Huang, B Klitzman, C
Kontos, BH Annex. A genetically
engineered plasmid encoding a zinc finger VEGF-activating transcription factor
induces angiogenesis in the rabbits with hind-limb ischemia. Molecular Therapy 7:855 part 2, 2003.
ABSTRACTS
(cont.)
157. Heitmann,
C., F Khan, KC Olbrich, AA Sharkawy, and B Klitzman. Sutureless anastomosis of a vein graft using
magnets. Plast. Surg. Res. Council, 2003.
158. Olbrich,
K.C., W. Bruno, D. Erdmann, R. Meade, L. Heller, B. Klitzman. Halofuginone inhibits capsule formation
surrounding silicone implants. Am Soc. Plast. Surg, 2003.
159. Dai Q., J. Huang, B. Klitzman, J.
Rokovich, B. Johnstone, C.D. Kontos, and B.H.
Annex. A zinc finger VEGF-activating
transcription factor induces therapeutic angiogenesis in rabbits with hind-limb
ischemia. Am Heart Assoc, 2003.
160.
Heitmann, C., F Khan, D Erdmann, KC Olbrich, AA Sharkawy, and B Klitzman. Resistance of chronic vein grafts
anastomosed using magnets. World Soc. Reconstr. Microsurg,
2003. Award for Best Paper.
161. Ko, JH, J Ross, H Awad, HI Hurwitz,
and B Klitzman. The effects of
ZD6474, an inhibitor of VEGF signaling, on cutaneous wound healing in
mice. Plast. Surg. Res. Council, 2004.
162. Prichard, HL, Reichert, and B
Klitzman. Adsorption of fibronectin
onto biomaterials. Soc. Biomat., 2004.
BOOKS, BOOK REVIEWS, AND BOOK CHAPTERS
1. Klitzman, B. Invited review of Laser
Doppler Flowmetry. ed. A.P. Shepherd. in The Physiologist, 1990.
2. Klitzman, B. and G. Ruff. Anastomotic thrombosis, alteration of the
coagulation cascade, and ischemia/reperfusion.
in Problems in Plastic Surgery.
ed. D. Serafin. J.B. Lippincott, pp.
25-37, 1991.
3. Yuen, J., B. Klitzman, and D. Serafin. Biomaterials
in Plastic Surgery. in Implantation Biology: The Host Response and
Biomedical Devices. ed. R.
Greco. CRC Press, pp. 191-228, 1994.
4. Sepka, R., D.
Serafin, and B. Klitzman. Plastic Surgery: Routine clinical use of
laser Doppler to monitor free tissue transfer.
in Laser Doppler Flowmeter
Applications. ed. G.V. Belcaro, U. Hoffman, A. Bollinger, and A.
Nicolaides. Med-Orion. London, 1994.
5. Problems in General Surgery: Biomaterials. ed. B.
Klitzman. Lippincott, 1994.
VIDEOTAPES
1. Klitzman, B. Clinical use of LDF in
cutaneous circulation and tissue transplantation. in Techniques in Laser Doppler Flowmetry, ed. B. Klitzman. Transonic Systems, 1992.
2. Klitzman, B. and R. Sepka. Clinical Use of the Laser Doppler Flowmeter:
Featuring Use in Plastic Surgical Flap Monitoring. Transonic Systems, 1993
INVITED PEER
REVIEWED COMMENTS
1. Young K.B., and B. Klitzman. The effects of acute hyperbaric oxygen therapy on axial pattern
skin flap survival when administered during and after total ischemia [Invited Discussion]. J.
Reconstr. Microsurg. 5:349-350,
1989.
2. Klitzman B. Modulation of ultraviolet light-induced epidermal damage:
Beneficial effects of tocopherol - Comment.
Plast. Reconstr. Surg.
102:1785-1786, 1998.
3. Erdmann, D. and B. Klitzman. Investigation
of TRAM flap oxygenation and perfusion by near-infrared reflection spectroscopy
and color-coded duplex sonography. Plast. Reconstr. Surg. 113(1):153-155, 2004.
SEMINARS, SYMPOSIA,
AND PANELS
1. June 1978,
Baxter‑Travenol Laboratories, Morton Grove, IL
2. June 1978,
Department of Physiology, Health Sciences Center, University of Arizona,
College of Medicine, Tucson, AZ
3. November 1979,
Departments of Physiology and Radiation Biology and Biophysics, School
of Medicine and Dentistry,
University of Rochester, Rochester, NY
4. March 1980, NATO
Advanced Study Institute on Biorheology, Houston,TX
5. September 1980,
Department of Physiology, College of Physicians and Surgeons, Columbia
University, New York, NY
6. September 1980,
Abteilung Physiologie der Rheinland Westphälische Technisches
Hochschüle, Aachen, West Germany
7. September 1980,
Departments of Physiology and Biophysics, Universiteit Limburg,
Maastricht, Netherlands
8. September 1980,
Janssen Pharmaceutica, Beerse, Belgium
9. September 1980,
Eleventh European Conference on Microcirculation,
Garmisch-Partenkirchen, West Germany
10. May 1981,
Department of Mechanical Engineering, University of Houston, Houston, TX
11. May 1981,
Department of Physiology and Biophysics, Louisiana State University School
of Medicine, Shreveport, LA
12. June 1982,
Gordon Research Conference on Water and Solute Exchange in the
Microvasculature, Plymouth, NH
13. January 1983,
Department of Physiology, University of Colorado, School of Medicine,
Denver, CO
14. May 1983,
Department of Medical Physiology, Texas A & M Univ., College Station, TX
15. August 1983,
Chairman, Scientific Session on Peripheral Blood Flow, Am. Physiol. Soc.
Meeting, Honolulu, HI
16. August 1983,
Keynote Speaker, Second Australia/New Zealand Symposium on the
Microcirculation, Leura NSW,
Australia
SEMINARS, SYMPOSIA,
AND PANELS (cont.)
17. November 1983,
Department of Biomedical Engineering, Louisiana Tech University,
Ruston, LA
18. September 1984,
Chairman, Scientific session on Microvascular Organization, Third
World Congress on Microcirculation,
Oxford University, Oxford, England
19. September 1984,
Symposium on Inhomogeneity of microcirculation in skeletal muscle,
Department of Physiology, University
of Birmingham, Birmingham, England
20. September 1984,
Department of Biophysics and Physiology, Rijksuniversiteit Limburg,
Maastricht, the Netherlands
21. September 1984,
Anatomisches Institüt, Universität Bern, Bern, Switzerland
22. September 1984,
Physiologisches Inst., Freie Universität Berlin, Berlin, West Germany
23. October 1984,
Laboratoire de Biophysique, Hôpital Fernand Vidal, Paris, France
24. May 1985,
Departments of Physiology and Surgery, Duke University, Durham, NC
25. September 1985,
Department of Medical Biophysics, University of Manchester Medical
School, Manchester, England
26. September 1985,
Department of Physiology, The Medical School, University of
Birmingham, Birmingham, England
27. October 1985,
Department of Physiology and Biophysics, Louisiana State University
School of Medicine, Shreveport, LA
28. March, 1986,
Southeastern Medical Dental Society, Crested Butte, CO
29. May, 1986,
Division of Plastic, Reconstructive, Maxillofacial, and Oral Surgery, Duke
University, Durham, NC
30. February, 1987,
Southeastern Medical Dental Society, Copper Mt., CO
31. June, 1987,
Division of Radiation Biophysics, Department of Radiology, Duke University
Medical Center, Durham, NC
32. June, 1987,
Division of Plastic, Reconstructive, Maxillofacial, and Oral Surgery, Duke
University Medical Center, Durham,
NC
SEMINARS, SYMPOSIA,
AND PANELS (cont.)
33. July, 1987,
Symposium on Clinical Laser Doppler Flowmetry, Fourth World Congress for
Microcirculation, Tokyo, Japan
34. April, 1988,
Radiation Research Society and North American Hyperthermia Group,
Philadelphia, PA
35. May, 1988,
Plastic Surgery Educational Foundation Symposium on Refinements in Free
Flap Surgery, New York, NY
36. May, 1988, Fed.
Am. Soc. Exp. Biol., Tutorial "Laser Doppler Flowmetry", Las Vegas,
NV
37. December, 1988,
Division of Plastic Surgery, Med. Col. Virginia, Virginia Commonwealth
University, Richmond, VA
38. February, 1989,
Dept. of Surgery, Univ. North Carolina - Chapel Hill, School of
Medicine, Chapel Hill, NC
39. September,
1989, Session Chairman, Am. Soc. for Reconstr. Microsurg., Seattle, WA
40. March, 1990,
Dept. of Cell Biology, Duke Univ. Sch. Med., Durham, NC
41. August, 1990,
Marine Biomedical Center, Duke Univ. Marine Laboratory, Beaufort, NC
42. February, 1991,
Department of Physiology & Biophysics, School of Medicine, University
of Louisville, Louisville, KY
43. March, 1991,
Division of Plastic and Reconstructive Surgery, University of Utah,
Salt Lake City, UT
44. September, 1991,
Chairman, Symposium on "Thrombosis and Microvascular Surgery", Fifth
World Congress for Microcirculation,
Louisville, KY
45. April, 1992,
FASEB, Chairman, Tutorial on "Techniques in Laser Doppler Flowmetry",
Anaheim, CA
46. July, 1992,
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial
Hospital, Taipei, Taiwan
47. September,
1992, Department of Biomedical Engineering, Duke Univ., Durham, NC
48. September,
1992, F.G. Hall Environmental Laboratory, Duke Univ. Med. Center,
Durham, NC
SEMINARS, SYMPOSIA,
AND PANELS (cont.)
49. November, 1992,
Division of Surgical Biology, University of Arizona, Tucson, AZ
50. July, 1993,
Symposium on "Advances in Hyperbaric Oxygen Therapy", Undersea and
Hyperbaric Medical Society, Halifax,
Nova Scotia, Canada
51. December, 1993,
NIH Sponsored Cardiovascular Sciences and Technology Symposium,
"Decreased thrombogenicity of
vascular prostheses", Washington, D.C.
52. May, 1994,
Morning Teaching Rounds, Division of Plastic and Reconstructive Surgery,
Duke University Medical Center,
Durham, NC
53. June, 1994,
Grand Rounds, Department of Surgery, Duke University Medical Center,
Durham, NC
54. September, 1994,
Department of Reconstructive and Plastic Surgery, M.D. Anderson
Cancer Center, University of Texas,
Houston, TX
55. September,
1994, Clinical Staff, Chang Gung Memorial Hospital, Taipei, Taiwan
(Measurement of Blood Flow: From
Laboratory to Clinic)
56. September,
1994, Department of Surgery, Chang Gung Memorial Hospital,
Taipei, Taiwan (Biocompatibility of
Microvascular Prostheses)
57. September,
1994, Department of Plastic and Reconstructive Surgery, Chang Gung
Memorial Hospital, Taipei, Taiwan
(Effects of Hyperbaric Oxygen on Normal and
Ischemic Tissue)
58. October, 1994,
Grand Rounds, Division of Otolaryngology-Head and Neck Surgery, Duke
University Medical Center, Durham,
NC (Rescue of irradiated bone periosteum and
metaphysis from late necrosis using
hyperbaric oxygen therapy)
59. October, 1995,
Grand Rounds, Division of Emergency Medicine Research, Carolinas
Medical Center, Charlotte, NC
(Development of engineered microvascular prostheses)
60. February, 1996,
Grand Rounds, Division of Plastic Surgery, Duke University Medical
Center, Durham, NC (Assessment of
tissue viability)
61. March, 1996,
Southeastern Medical-Dental Society, Crested Butte, CO (Tissue
Engineering: Designer organs are on
the drawing board)
62. March, 1996, Grand
Rounds, Division of Otolaryngology-Head and Neck Surgery, Duke
University Medical Center, Durham,
NC (Improved biocompatibility of vascular
prostheses)
SEMINARS, SYMPOSIA,
AND PANELS (cont.)
63. May, 1996,
Third Endosurgery Symposium: Minimally Invasive and Endoscopic Plastic
Surgery Seminar (Live animal laser
surgery training)
64. October, 1996, Grand Rounds, Division of
Plastic Surgery, Duke University Medical
Center, Durham, NC (New developments
in microvascular physiology)
65. November/December,
1996, Department of Plastic and Reconstructive Surgery, Chang Gung
Memorial
Hospital, Taipei, Taiwan; 20th Anniversary Divisional Celebration and
Retirement Celebration of Dr. Samuel Noordhof (Six lectures on various topics,
including tissue engineering, microvascular physiology, oxygen delivery, cell
communication in the blood vessel wall, endothelial cell transplant)
66. March, 1997, Grand Rounds, Division of
Plastic Surgery, Duke University Medical
Center, Durham, NC (Tissue
Engineering for Plastic Surgeons)
67. July, 1997,
Inspire Pharmaceuticals, Research Triangle Park, NC (Wound Healing: O1d
and new animal models)
68. July, 1997,
Grand Rounds, Division of Plastic Surgery, Duke University Medical Center,
Durham, NC (Assessment of tissue
viability)
69. August, 1997,
Endoscopic Orthopedic Trauma, Duke University Medical Center, Durham, NC
(Minimally invasive tissue expansion)
70. April, 1998,
Chair, Scientific Session, Plastic Surgery Research Council, Loma Linda
University, Loma Linda, CA
71. April, 1998,
Chair, Vascular development in engineered tissues: symposium, Experimental
Biology ’98, San Francisco, CA
72. April, 1998,
Chair, Tissue Engineering Symposium at Biotech ’98, Research Triangle Park, NC
73. April, 1998,
Grand Rounds, Division of Plastic Surgery, Duke University Medical Center,
Durham, NC (Tissue engineering)
74. June, 1998,
Chair and Organizer, North Carolina Tissue Engineering Interest Group, Research
Triangle Park, NC
75. July, 1998,
Grand Rounds, Division of Plastic Surgery, Duke University Medical Center,
Durham, NC (Assessment of tissue
viability)
76. January, 1999,
Panel, Microsurgical Training: Past, Present and Future, Am. Soc. Reconstr.
Microsurg., Kamuela, HI
SEMINARS, SYMPOSIA,
AND PANELS (cont.)
77. April, 1999,
Eugene M. Landis Award Lecture. Introduction of Dr. Marcos Intaglietta.
Experimental Biology ’99,
Washington, D.C.
78. September, 1999, Invited speaker, 12th
Bodensee Conference on Microcirculation, Lake
Constance, Germany (Wound-induced
angiogenesis: A clinical model)
79. November, 1999, Visiting Professor,
UNC-Charlotte, Department of Biological Sciences,
Charlotte, NC
80. April, 2000,
Chair, Tissue Repair and Regeneration Symposium at Biotech 2000,
Research Triangle Park, NC
81. June, 2000, Invited Speaker, Symposium on
Clinical Intravital Microscopy, European
Conference on Microcirculation,
Stockholm, Sweden.
82. March, 2001,
Chair, Clinical Applications of Intravital Microscopy, Experimental Biology ‘01
Orlando, FL
83. August, 2001, Invited Speaker, Symposium on
Clinical Intravital Microscopy,
7th World Congress for
Microcirculation, Sydney, Australia
84. October-November, 2001,
Featured Speaker, Inaugural Congress of the World Society for
Reconstructive Microsurgery, Chang Gung Memorial Medical Center,
Taipei, Taiwan
85. June, 2001, Initial Review Group (Study
Section), NIH
86. June, 2003, Chair, Experimental Forum, World
Society for Reconstructive Microsurgery,
Heidelberg, Germany
87. October, 2003, Initial Review Group (Study
Section), NIH
88. March, 2004, Seminar,
Biomedical Engineering, Duke University Medical Center
89. March, 2004, Visiting Professor, M.D.
Anderson Cancer Center, Houston, TX
90. April, 2004. Visiting Professor, Mansoura
University, Egypt.
SERVICE
Departmental
1983‑5 Graduate Studies Committee
1983‑5 Director of Departmental
Seminars
1985-
Director, Plastic Surgery Research Laboratories
1986-95 Charter Member, Divisional
Endowment Board
1993-1999
Chairman, Instructional Technologies Committee, Medical Physiology
1985-96 AAALAC Accreditation of Animal
Holding Facility within Laboratory
1995-2002
Divisional Web Site: webmaster and web site liaison for lay inquiries
Institutional
1982‑4 Library Committee, Louisiana
State University School of Medicine
1983‑4 Basic Science Representative
to Faculty Council, (alternate), Louisiana St Univ Sch Med
1983‑4 Grant Review Committee,
Stiles Research Fund, Louisiana State Univ Sch Med
1984‑5 Institutional Review Board
for Human Experimentation, Louisiana State Univ Sch Med
1984‑5 Basic Science Representative
to Faculty Council, Louisiana State Univ Sch Med
1984‑5 Basic Science Representative
to Joint Council, Louisiana State Univ Sch Med
1988-97
F. G. Hall Environmental Laboratory, Scientific Advisory Board, Duke
University
1996-2001
Advisory Board, Center for Cellular and Biosurface Engineering, Duke
University
2001-
Steering Committee, Center for Biomolecular and Tissue Engineering, Duke
Univ
2003-
Director, Biomedical Engineering Study Program for 3rd-year
Med Students, Duke Univ
State
1985
American Heart Association, Louisiana Affilliate, Research Committee
1997-99
Founder, North Carolina Tissue Engineering Interest Group
1997-
Animal Care and Use Committee, vol. scientist member, Piedmont Research
Corp., NC
2000
Chair, “Future Potential of Tissue Engineering”, Biotech 2000, NC
National
and International
1979-
Journal Editorial Boards:
Journal
of Reconstructive Microsurgery; Associate Editor, 1986-1996
Cell
Transplantation
Microcirculation
Microvascular
Research
Guest Reviewer:
American Journal of Physiology,
several sections
Annals of Biomedical Engineering
Blood Vessels
Circulation Research
Journal of Applied Physiology
Journal of Investigative
Dermatology
Journal of Laboratory and Clinical
Medicine
Journal of Orthopaedic Research
Journal of Physiology
International Journal of Radiation
Research
SERVICE; National
and International (cont.)
Journal Editorial Board; Guest Reviewer (cont.)
International Journal of
Hyperthermia
Life Sciences
Microcirculation
Microsurgery
Microvascular Research
Pflüger's Archiv, European Journal
of Physiology
Plastic and Reconstructive Surgery
Radiation Research
1983 Chairman, "Peripheral Blood
Flow" session, American Physiological Society
1983‑4
Program Committee, Microcirculatory Society, Inc.
1984‑7
Membership Committee, Microcirculatory Society, Inc.
1984‑ Fellow, Council on Circulation, American
Heart Association
1984 Chairman, "Microvascular
Organization" session, 3rd World Congress
for Microcirculation,
Oxford University, UK
1985 Cardiovascular and Renal Study Section,
NIH
1986 Special Study Section, Reviewer, NIH
1986-96 Associate
Editor, Journal of Reconstructive
Microsurgery
1987 Chairman, "Laser Doppler
Flowmetry" session, Fourth World Congress
for Microcirculation,
Keio University, Tokyo
1988 Faculty, Plastic Surgery Educational
Foundation Workshop
1989 Hearing Research Study Section, Guest
Reviewer, NIH Public Advisory Group
1989 Chairman, Scientific Session, American Soc.
for Reconstructive Microsurgery, Seattle, WA
1990 Surgery, Anesthesiology, and Trauma Study
Section, Guest Reviewer, NIH
1990 Chairman,
"Bioengineering of the Heart and Circulation" session, Biomedical Engineering Society/FASEB, Washington, D.C.
1990 Special Reviewer, Health Effects Institute,
Cambridge, MA
1991 Special Reviewer, Health Effects Institute,
Cambridge, MA
1991 Organizer and Chair, Symposium on
"Thrombosis and Microvascular Surgery",
Fifth World Congress for Microcirculation,
Louisville, KY
1992 Research
Advisor, Chang Gung Memorial Hospital, Taipei, Taiwan
1992 Chairman,
"Laser Doppler Flowmetry" symposium, FASEB, Anaheim, CA
1993-7 Secretary, The Microcirculatory
Society
1993-7 Liaison Committee, The
Microcirculatory Society
1993-7 Publications Committee, The
Microcirculatory Society, ex officio
1993-7 Executive Committee, The
Microcirculatory Society
1994- Editorial
Board, Cell Transplantation
1994 American
Heart Association, ad hoc grant review
1995 Charter
Member, Tissue Engineering Society
1995 Jewish
Hospital Research Foundation, Louisville, KY; Research Grant Review
1996 Lecture
Series (7 lectures), Research Advances in Plastic and Reconstructive Surgery,
Chang Gung Memorial
Hospital, Taipei, Taiwan
1996-7 Organizing Cmte, Vascular Biology '97;
cooperative meeting among The Microcirc.
Soc., North Am. Vasc. Biol. Org., Am. Heart
Assoc., and Am. Soc. Invest. Path.
SERVICE;
National and International (cont.)
1997-2000
Jewish Hospital Research Foundation, Louisville, KY; Research Grant
Reviewer
1997-8 President-elect and Program Chair, The
Microcirculatory Society
1997-8 Scientific Programming Committee,
Plastic Surgery Research Council
1997-8 Programming Committee, Experimental
Biology '98 (FASEB)
1998-9 President, The Microcirculatory
Society
1999-2000 Chair, Long-range Planning
Committee, The Microcirculatory Society
2001 Featured Speaker, First World Society
for Reconstructive Microsurgery, Taipei, Taiwan
2001-2006 Microcirculation International Liaison
Committee
2002 Initial Review Group (Study Section),
NIH
2003 Scientific Reviewer, 2nd
World Society for Reconstructive Microsurg., Heidelberg, Germany
2003 Initial Review Group (Study Section),
NIH
CORPORATE
ACTIVITIES
Scientific
Consultant, Ventrica, Inc., Fremont, CA, 1999-
FastTrack course,
Council for Entrepreneurial Development, Research Triangle Park, NC, 1999
US Patent
6,013,122; “Tattoo Inks”
Secretary/Treasurer
and Co-Founder, Option Technologies, Inc. Durham, NC 1998-2003; acquired by
Freedom-2 LLC in 2002. Scientific
Advisory Board and Member of Freedom-2, LLC 2002-
COMMUNITY
ACTIVITIES
Forest View
Elementary School PTA; Science Advisory Committee 1995-7; Concessions
Committee, volunteer, 1988-98; Co-chair, 1995-6; Chair, 1996-7
Habitat for
Humanity, Durham, 1996
Institutional
Animal Care and Use Committee, Volunteer Scientist Representative,
Piedmont Research Center, 1997-2005
Travel Organizer and
Chaperone, Pines of Carolina Girl Scout Chapter service trip to Phuket,
Thailand to assist with education
and health care for ChildWatch, 2002
Immaculate
Conception Catholic Church; Sponsor, Rite of Christian Initiation for Adults,
1997-2001; Chair, Volunteers for
Special Olympics World Summer Games, 1998-99;
Rite of Christian Initiation for
Adults: Sponsor 1997-2001, Sponsor Coordinator 2000-02,
Co-Director 2002- ; Invited Presenter, Regional RCIA Conference, 2002;
Eucharistic Minister and Coordinator,
2000-
REFERENCES
L. Scott Levin, M.D.
Professor and Chief
Division of Plastic, Reconstructive,
Maxillofacial and Oral Surgery and
Division of Orthopedic Surgery
Duke University Medical Center
Durham, North Carolina 27710-3974
Telephone: (919) 681-5079
email: levin001@mc.duke.edu
Donald Serafin, M.D.
Professor and Chief Emeritus
Division of Plastic, Reconstructive,
Maxillofacial and Oral Surgery
Duke University Medical Center
Durham, North Carolina 27710-3372
Telephone: (919) 684‑3347
Brian R. Duling, Ph.D.
Professor and Vice-Chairman
Department of Molecular Physiology
and Cellular Biophysics
Director, Cardiovascular Research Center
University of Virginia School of Medicine
Charlottesville, Virginia 22908
Telephone: (804) 924‑5092
email:brd@med.virginia.edu
Paul C. Johnson, Ph.D.
Professor, Department of Bioengineering
University of California at San Diego
La
Jolla, CA 92093-6896
Telephone: (619)534-5686
email: pjohnson@bioeng.ucsd.edu