Selected Publications
Here is a selection of our recent papers.
Selected Refereed Papers
2017 Gao Y and Katz DF. Multicompartmental pharmacokinetic model of tenofovir delivery to the rectal mucosa by an enema. PLoS One 12(1):e0167696.
2017 Chuchuen O, Maher JR, Simons MG, Peters JJ, Wax AP, and Katz DF. Label-free measurements of tenofovir diffusion coefficients in a microbicide gel using Raman spectroscopy. Journal of Pharmaceutical Sciences 106: 639 - 644.
2016 Funke C, MacMillan K, Ham A, Szeri AJ, and Katz DF. Coupled gel spreading and diffusive transport models describing microbicidal drug delivery. Chemical Engineering Science 152: 12 - 20.
2016 Jarrett AM, Gao Y, Hussaini MY, Cogan NG, and Katz DF. Sensitivity analysis of a pharmacokinetic model of vaginal anti-HIV microbicide drug delivery. Journal of Pharmaceutical Sciences 105: 1772 - 1778.
2016 Guthrie KM, Dunsiger S, Vargas SE, Fava JL, Shaw JG, Rosen RK, Kiser PF, Kojic EM, Friend DR, and Katz DF. Perceptibility and the "choice experience": user perceptions and experiences inform vaginal prevention product design. AIDS Research and Human Retroviruses 32: 1022 - 1030.
2015 Ham AS, Nugent ST, Peters JJ, Katz DF, Shelter CM, Dezzutti CS, Boczar AD, Buckheit KW, and Buckheit RW. The rational design and development of a dual chamber vaginal / rectal microbicide gel formulation for HIV prevention. Antiviral Research 102: 153 - 164.
2015 Maher JR, Chuchuen O, Henderson MH, Kim S, Rinehart MT, Kashuba ADM, Wax A, and Katz DF. Co-localized confocal Raman spectroscopy and optical coherence tomography (CRS-OCT) for characterizing analytes in biological tissues. Biomedical Optics Express 6: 2022 - 2035.
2015 Katz DF, Yuan A, and Gao Y. Vaginal drug distribution modeling. Advanced Drug Delivery Reviews 92: 2 - 13.
2015 Gao Y, Yuan A, Chuchuen O, Ham A, Yang KH, and Katz DF. Vaginal deployment and tenofovir delivery by a microbicide gel. Drug Delivery and Translational Research 5: 279 - 294.
2014 Maher JR, Matthews TE, Reid AK, Katz DF, and Wax A. Sensitivity of coded aperture Raman spectroscopy to analytes beneath turbid biological tissue and tissue-simulating phantoms. Journal of Biomedical Optics 19 (11) 117001: 1 - 7.
2014 Morrow KM, Fava JL, Rosen RK, Shaw JG, Kojic EM, Kiser PF, Friend DR, and Katz DF. Designing preclinical perceptibility measures to evaluate topical vaginal gel formulations: relating user sensory perceptions and experiences to formulation properties. AIDS Research and Human Retroviruses 30: 78 - 91.
2014 Morrow KM, Underhill K, van den Berg JJ, Vargas S, Rosen RK, and Katz DF. User-identified gel characteristics: a qualitative exploration of perceived product efficacy of topical vaginal microbicides. Archives of Sexual Behavior 43: 1459 - 1467.
2014 Katz DF. Biophysics, drug transport modeling and microbicides, in Drug Delivery and Development of Anti-HIV Microbicides. J das Neves and B Sarmento, Eds. Pan Stanford Publishing, Singapore.
2013 Chuchuen O, Henderson MH, Sykes C, Kim MS, Kashuba ADM, and Katz DF. Quantitative analysis of microbicide concentrations in fluids, gels, and tissues using confocal Raman spectroscopy. PLoS ONE 8: e85124.
2013 Van den Berg V, Morrow K, Rosen R, Bregman D, Thompson L, Jensen K, Kiser P, Katz D, Buckheit K, and Buckheit R. "Set it and forget it": Women's perceptions and opinions of long-acting topical vaginal gels. AIDS and Behavior 1007/s10461-013-0652-4.
2013 Morrow KM, Fava JL, Rosen RK, Shaw JG, Kojic EM, Kiser PF, Friend DR, and Katz DF. Designing preclinical perceptibility measures to evaluate topical vaginal gel formulations: Relating user sensory perceptions and experiences to formulation properties. AIDS Research and Human Retroviruses 29: 1-14.
2013 Drake TK, Shah T, Peters JJ, Wax A, and Katz DF. Measuring dilution of microbicide gels with optical imaging. PLoS ONE 8: e82213.
2013 Gao Y and Katz DF. Multicompartment pharmacokinetic model of Tenofovir delivery by a vaginal gel. PLoS ONE e0074404.
2013 Tasoglu S, Katz DF, Rohan LM, and Szeri AJ. Transient spreading and swelling behavior of a dissolved anti-HIV microbicide bearing film. Physics of Fluids 25:031901.
2012 Drake TK, DeSoto MG, Peters JJ, Henderson MH, Thiele B, Bishop TS, Murtha AP, Katz DF, and Wax A. In vivo optical imaging of human vaginal gel thickness distributions with a probe-based, dual modality instrument. Journal of Biomedical Optics 17:116014.
2012 Tasoglu S, Katz DF, and Szeri AJ. Transient spreading and swelling behavior of a gel deploying an anti-HIV topical microbicide. Journal of Non-Newtonian Fluid Mechanics 187-188:36-42.
2012 Romero JF, Abraham C, Rodriguez A, Kizima L, Jean-Pierre N, Menon R, Begay O, Seidor S, Ford B, Gil P, Peters J, Katz D, Robbiani M, and Zydowsky T. Zinc acetate/carrageenan gels exhibit potent activity in vivo against high dose HSV-2 vaginal and rectal challenge. Antimicrobial Agents and Chemotherapy 56: 358-368.
2012 Kiser PF, Smith E, Fabian J, Damian FR, Peters JJ, Katz DF, Elbendy H, Clark MR, and Friend DR. Design of tenofovir/UC781 combination microbicide vaginal gels. Journal of Pharmaceutical Sciences 101: 1852-1864.
2011 Rinehart MT, Drake TK, Robles FE, Rohan LC, Katz DF, and Wax A. Time resolved imaging refractometry of microbicidal films using quantitative phase microscopy. Journal of Biomedical Optics Letters 16: 12510, 1–3.
2011 Drake TK, DeSoto MG, Peters JJ, Henderson MH, Murtha AP, Katz DF, and Wax A. Design and validation of a multiplexed low coherence interferometry instrument for in vivo clinical measurement of microbicide gel thickness distribution. Biomedical Optics Express 2 (10): 2851.
2011 Tasoglu S, Park SC, Peters JJ, Katz DF, and Szeri AJ. The consequences of yield stress on deployment of a non-Newtonian anti-HIV microbicide gel. Journal of Non-Newtonian Fluid Mechanics 166(19-20): 1116-1122.
2011 Katz DF, Gao Y, and Kang M. Using modeling to help understand vaginal microbicide functionality and create better products. Drug Delivery and Translational Research 1:256-276.
2011 Tasoglu S, Peters JJ, Park SC, Verguet S, Katz DF, and Szeri A. The effects of inhomogeneous boundary dilution on the coating flow of an anti-HIV microbicide vehicle. Physics of Fluids 23: 0931201.
2011 Begay O, Jean-Pierre N, Abraham C, Chudolij A, Seidor S, Rodriquez A, Ford B, Henderson M, Katz D, Zydowsky T, Robbiani M, and Fernandez-Romero J. Identification of personal lubricants that can cause rectal epithelial cell damage and enhance HIV-1 replication in vitro. AIDS Research and Human Retroviruses. 27(9): 1019-1024.
2010 Mahalingam A, Smith E, Fabian J, Damian DR, Peters J, Clark MR, Friend DR, Katz DF, and Kiser PF. Design of a semisolid vaginal microbicide gel by relating composition to properties and performance. Pharmaceutical Research 27: 2478-2491.
2010 Lai BE, Geonnotti AR, DeSoto MG, Montefiori DC, and Katz DF. Semi-solid gels function as physical barriers to human immunodeficiency virus transport in vitro. Antiviral Research 88(2): 143-151.
2010 Geonnotti AR and Katz DF . Compartmental transport model of microbicide delivery by an intravaginal ring. Journal of Pharmaceutical Sciences 99(8): 3514-3521.
2010 Jay JI, Lai BE, Myszka DG, Mahalingam A, Langheinrich K, Katz DF, and Kiser PF. Multivalent benzoboroxole functionalized polymers as gp120 glycan targeted microbicide entry inhibitors. Molecular Pharmaceutics 7(1): 116-129.
2009 Lai BE, Henderson MH, Peters JJ, Walmer DK, and Katz DF. Transport theory for HIV diffusion through in vivo distributions of topical microbicide gels. Biophysical Journal 97(9):2379-2387.
2008 Szeri AJ, Park SC, Verguet S, Weiss A, and Katz DF. A model of trans-luminal flow of anti-HIV microbicide vehicles: combined elastic squeezing and gravitational sliding. Physics of Fluids 20(8):083101.
2008 Geonnotti AR, Furlow MJ, Wu T, DeSoto MG, Henderson MH, Kiser PF, and Katz DF. Measuring macrodiffusion coefficients in microbicide hydrogels via postphotoactivation scanning. Biomacromolecules 9(2):748-751.
2008 Lai BE, Xie YQ, Owen DH, and Katz, DF. Dilution of microbicide gels with vaginal fluid and semen simulants: effect on rheological properties and coating flow. Journal of Pharmaceutical Sciences 97(2): 1028-1036.
2007 Henderson MH, Couchman GM, Walmer DK, Peters JJ, Owen DH, Brown MA, Lavine ML and Katz DF. Optical imaging and analysis of human vaginal coating by drug delivery gels. Contraception 75: 142-151.
2007 Owen DH, Peters JJ, Kieweg SL, Geonnotti AR, Schnaare RL, and Katz DF. Biophysical analysis of prototype microbicidal gels. Journal of Pharmaceutical Sciences 96: 661-669.
2007 Gupta KM, Barnes SR, Tangaro RA, Roberts MC, Owen DH, Katz DF, and Kiser PF. Temperature and semen sensitive hydrogels: an approach towards smart vaginal microbicide vehicles. Journal of Pharmaceutical Sciences 96: 670-681.
2007 Kieweg, SL and Katz, DF . Interpreting properties of microbicide drug delivery gels: analyzing deployment due to squeezing. Journal of Pharmaceutical Sciences 96(4): 835-850.
2006 Braun K, Henderson M, Katz D, and Wax A. Label-free measurement of microbicidal gel thickness using low coherence interferometry. Journal of Biomedical Optics 11(2): 020504.
2006 Geonnotti AR and Katz DF . Dynamics of HIV neutralization by a microbicide formulation layer: biophysical fundamentals and transport theory. Biophysical Journal 91(6): 2121-2130.
2006 Kieweg SL and Katz DF. Squeezing flows of vaginal gel formulations relevant to microbicide drug delivery. Journal of Biomechanical Engineering 128: 540-553.
2005 Geonnotti AR, Peters JJ, and Katz DF. Erosion of microbicide formulation coating layers: effects of contact and shearing with vaginal fluid or semen. Journal of Pharmaceutical Sciences 94(8): 1705-1712.
2005 Owen DH and Katz DF. A review of the properties of human semen and formulation of a semen simulant. Journal of Andrology 26(4): 459-469.
2005 Henderson MH, Peters JJ, Walmer DK, Couchman GM. and Katz DF. Optical instrument for measurement of vaginal coating thickness by drug delivery formulations. Virtual Journal of Biological Physics Research 9 (March 15).
2005 Henderson MH, Peters JJ, Walmer DK, Couchman GM, and Katz DF. Optical instrument for measurement of vaginal coating thickness by drug delivery formulations. Review of Scientific Instruments 76:034302.
2004 Walmer DK, Littman E, Rodriguez G, Venero N, Henderson M, Katz D, Edward R, and MacFayden A. Portable colposcopy in low-resource settings. J AIDS 35: Suppl 2, S1-S4.
2004 Kieweg SL, Geonnotti AR, and Katz DF. Gravity-induced coating flows of vaginal gel formulations: in vitro experimental analysis. Journal of Pharmaceutical Sciences 93: 2941-2952.
2003 Owen DH, Peters JJ, Lavine MJ, and Katz DF. Effect of temperature and pH on contraceptive gel viscosity. Contraception 67: 57-64.
2001 Owen DH, Peters JJ, and Katz DF. Comparison of the rheological properties of Advantage-S and Replens. Contraception 64: 393-396.
2000 Owen DH, Peters JJ, and Katz DF. Rheological properties of contraceptive gels. Contraception 62: 321-326.
1999 Owen DH, Dunmire EN, Plenys AM, and Katz DF. Factors influencing nonoxynol-9 permeation and bioactivity in cervical mucus. Journal of Controlled Release 60: 23-34.
1999 Dunmire EN, Plenys AM, and Katz DF. Spectrophotometric analysis of molecular transport in gels. Journal of Controlled Release 57:127-140.
1999 Owen DH and Katz DF. A vaginal fluid simulant. Contraception 59: 91-95.
1999 Fulford GR, Katz DF, and Powell RL. Swimming of spermatozoa in a linear viscoelastic fluid. Biorheology 35: 295-309.
1998 Katz DF, Henderson MH, Owen DH, Plenys AM, and Walmer DK. What is needed to advance vaginal formulation technology? Vaginal Microbicide Formulations Workshop, WF Rencher (Ed.), Lippencott-Raven, Philadelphia, pp. 90-99.
1998 Dunson TR, Blumental PD, Alvarez F, Brache S, Cochon L, Dalberth B, Glover L, Remsburg R, Vu K, and Katz DF. Timing of onset of contraceptive effectiveness in NORPLANT® implant users. I. Changes in cervical mucus. Fertility and Sterility 69: 256-266.
1997 Katz DF, Slade DA, and Nakajima SJ. Analysis of preovulatory changes in cervical mucus hydration and sperm penetrability. Advances in Contraception 13: 143-151.
1997 Dunmire EN and Katz DF. Alteration of human sperm kinematics in cervical mucus due to nonoxynol-9. Contraception 55:209-217.
1995 Dunmire EN and Katz DF. Measurement and modulation of nonoxynol-9 permeation into human cervical mucus. Contraception 55: 115-122.
1994 Lewis JL, Burns SM, Samuels SJ, Powell RL, and Katz DF. Calibration and error analysis of a new magnetic sphere microrheometer. Review of Scientific Instruments 65: 3268-3275.
1994 Dunmire EN and Katz DF. Kinematic response of human spermatozoa to nonoxynol-9. Biology of Reproduction 50: 903-911.
1993 Katz DF and Dunmire EN. Cervical mucus: problems and opportunities for drug delivery via the vagina and cervix. Advanced Drug Delivery Reviews 11: 385-401.
