Bowes Rickman Laboratory
Duke University Eye Center








Selected Publications

Bowes Rickman C., Ebright JN, Zavodni ZJ, Yu L, Wang T, Daiger SP, Wistow G, Boon K and Hauser MA. Defining the Human Macula Transcriptome and Candidate Retinal Disease Genes using EyeSAGE. Invest Ophthalmol Vis Sci. 2006, in press.

Rosenthal R, Malek G, Salomon N, Peill-Meininghaus M, Coeppicus L, Wohlleben H, Wimmers S, Bowes Rickman C, Strauss O. The fibroblast growth factor receptors, FGFR-1 and FGFR-2, mediate two independent signalling pathways in human retinal pigment epithelial cells. Biochem Biophys Res Commun. 2005 Nov 11;337(1):241-7. PMID: 16188231

Malek G, Johnson LV, Mace BE, Saloupis P, Schmechel DE, Rickman DW, Toth CA, Sullivan PM, Bowes Rickman C. Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11900-5. Epub 2005 Aug 3. PMID: 16079201

Cahill MT, Mruthyunjaya P, Bowes Rickman C, Toth CA. Recurrence of retinal pigment epithelial changes after macular translocation with 360 degrees peripheral retinectomy for geographic atrophy. Arch Ophthalmol. 2005 Jul;123(7):935-8. PMID: 16009834

Yang P, Wiser JL, Peairs JJ, Ebright JN, Zavodni ZJ, Bowes Rickman C, Jaffe GJ. Human RPE expression of cell survival factors. Invest Ophthalmol Vis Sci. 2005 May;46(5):1755-64. PMID: 15851579

Rosenthal, R, Wohlleben, H, Malek, G, Schlichting, L, Thieme, H, Rickman, CB, Strauss, O (2004) Insulin-like growth factor-1 contributes to neovascularization in age-related macular degeneration. Biochem Biophys Res Commun. 323(4):1203-8.

Thompson, CL, Bowes Rickman, C , Shaw, SJ, Ebright, JN, Kelly, U, Sancar, A and Rickman, DW (2003) Expression of the Blue-Light Receptor Cryptochrome in the Human Retina. Invest Ophthal Vis Sci. 44, 4515-4521

Ebright, J.N. and Bowes Rickman, C (2003) Rapid, Reproducible Real-Time Quantitative RT-PCR Using theiCycler iQ Real-Time PCR Detection System and iQ Supermix. BioRadiations 110:32-35

Yarovinsky TO, Rickman DW, Diamond RH, Taub R, Hageman GS, Bowes Rickman C. Expression of the protein tyrosine phosphatase, phosphatase of regenerating liver 1, in the outer segments of primate cone photoreceptors. Brain Res Mol Brain Res. 2000 Apr 14;77(1):95-103

Rickman DW, Nacke RE, Bowes Rickman C. Characterization of the cell death promoter, Bad, in the developing rat retina and forebrain. Brain Res Dev Brain Res. 1999 Jun 8;115(1):41-7

Rickman DW, Bowes Rickman C. Suppression of trkB expression by antisense oligonucleotides alters a neuronal phenotype in the rod pathway of the developing rat retina. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12564-9

Bowes C, Li T, Frankel WN, Danciger M, Coffin JM, Applebury ML, Farber DB. Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2955-9

Bowes C, Li T, Danciger M, Baxter LC, Applebury ML, Farber DB. Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase. Nature. 1990 Oct 18;347(6294):677-80



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