VanDongen, Antonius M.J. |
POSITION TITLE Associate Professor of Pharmacology & Cancer Biology |
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Education |
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INSTITUTION AND LOCATION |
DEGREE |
YEAR |
FIELD OF STUDY |
University of Utrecht, The Netherlands University of Utrecht, The Netherlands University of Leiden, The Netherlands |
B.S. M.S. PhD |
1979 1982 1988 |
Biology and Physics Biology and Physics Biophysics |
Positions Held | |||
86-89 | Research Associate |
Dept Mol Physiology & Biophysics |
Baylor College of Medicine, Houston Texas. |
89-92 | Research Instructor |
Dept Mol Physiology & Biophysics |
Baylor College of Medicine, Houston Texas. |
92-98 | Assistant Professor |
Dept Pharmacology & Cancer Biology |
Duke University Medical Center, Durham, North Carolina. |
98-present | Associate Professor |
Dept Pharmacology & Cancer Biology |
Duke University Medical Center, Durham, North Carolina. |
99-08 | Associate Professor |
Dept Neurobiology |
Duke University Medical Center, Durham, North Carolina. |
08-present | Associate Professor | Program in Neuroscience and Behavioral Disorders | Duke-NUS Medical School, Singapore. |
Research Papers |
Van Dongen AMJ and Bretschneider F, 1984, Functioning of catfish electroreceptors: bursting discharge pattern of Kryptopterus electroreceptors elicited by microelectrode impalement, Comp. Biochem. Physiol. 77A: 647-650. Reprint Citations VanDongen AMJ, VanErp MG and Voskuyl RA, 1986, Valproate reduces excitability by blockage of sodium and potassium conductance, Epilepsia 27: 177-182. Abstract Reprint Citations Habets AMMC, Van Dongen AMJ, van Huizen F and Corner MA, 1987, Spontaneous neuronal firing patterns in fetal rat cortical networks during development in vitro: a quantitative analysis, Exp. Brain Res 69: 43-52. Abstract Reprint Citations VanDongen AMJ, Codina J, Olate J, Mattera R, Joho R, Birnbaumer L and Brown AM, 1988, Newly identified brain potassium channels gated by the guanine nucleotide binding protein GO, Science 242: 1433-1437. Abstract Citations Frech GC, VanDongen AMJ, Schuster G, Brown AM and Joho RH, 1989, A novel rat brain potassium channel with delayed rectifier properties isolated through expression cloning, Nature 340: 642-645. Abstract Reprint Citations Schubert B, VanDongen AMJ, Kirsch GE, and Brown AM, 1989, Beta-adrenergic inhibition of cardiac sodium channels by dual G protein pathways, Science 245: 516-519. Abstract Citations Joho RH, Moorman JR, VanDongen AMJ, Kirsch GE, Silberberg H, Schuster G and Brown AM, 1990, Toxin and kinetic profile of rat brain type III sodium channels expressed in Xenopus oocytes, Mol. Brain Res. 7: 105-113. Abstract Reprint Citations Moorman JR, Kirsch GE, VanDongen AMJ, Joho RH and Brown AM, 1990, Fast and slow gating of sodium channels encoded by a single mRNA, Neuron 4: 243-252. Abstract Reprint Citations Schubert B, VanDongen AMJ, Kirsch GE, and Brown AM, 1990, Inhibition of cardiac Na currents by isoproterenol, Am. J. Physiol. 258: H977-H982. Abstract Reprint Citations Van Erp MG, VanDongen AMJ and Van den Berg RJ, 1990, Voltage-dependent action of Valproate on potassium channels in frog node of Ranvier, Eur. J. Pharmacol. 184: 151-161. Abstract Reprint Citations VanDongen AMJ, Frech GC, Drewe JA, Joho RH and Brown AM, 1990, Alteration and restoration of K channel function by deletions at the N- and C-termini. Neuron 5: 433-443. Abstract Reprint Citations Taglialatela M, VanDongen AMJ, Drewe JA, Joho RH, Brown AM and Kirsch GE, 1991, Patterns of internal and external TEA block in four homologous K+ channels, J. Mol. Pharmacol. 40: 299-307. Abstract Reprint Citations Wood MW, VanDongen HMA and VanDongen AMJ, 1995, Structural conservation of ion conduction pathways in K channels and glutamate receptors. Proc. Natl. Acad. Sci. USA 92(11): 4882-4886. Abstract Citations Reprint VanDongen, AMJ, 1996, A new algorithm for idealizing single ion channel data containing multiple unknown conductance levels, Biophys. J. 70: 1303-1315. Abstract Citations Reprint Wood, MW, VanDongen, HMA and VanDongen AMJ, 1996, The 5'-untranslated region of the N-methyl-D-aspartate receptor NR2A subunit controls efficiency of translation, J. Biol. Chem. 271(14): 8115-8120. Abstract Citations Reprint Krovetz HS, VanDongen HMA and VanDongen AMJ, 1997, Atomic distance estimates from disulfides and high- affinity metal binding sites in a K channel pore, Biophys. J. 72: 117-126. Abstract Reprint Citations Chapman ML, VanDongen HMA and VanDongen AMJ, 1997, Activation-dependent subconductance levels in the drk1 K channel suggest a subunit basis for ion permeation and gating, Biophys. J. 72: 708-719. Abstract Reprint Citations Wood, MW, VanDongen, HMA and VanDongen AMJ, 1997, An alanine residue in the M3-M4 linker lines the glycine binding pocket of the NMDA receptor, J. Biol. Chem. 272(6): 3532-3537. Abstract Reprint Citations Wood, MW, VanDongen HMA and VanDongen AMJ, 1999, A mutation in the glycine binding pocket of the N-methyl-D-aspartate receptor NR1 subunit alter agonist efficacy, Mol. Brain Res. 73: 189-192. Abstract Reprint Citations Courtney KD, Grove M, VanDongen HMA, VanDongen AMJ, LaMantia A-S, and Pendergast AM, 2000, Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system, Mol. Cell. Neurosci 16(3):244-257. Reprint Citations Chapman ML, Krovetz HS and VanDongen AMJ, 2001, GYGD motifs in neighboring subunits interact to determine K channel selectivity, J. Physiol. 530: 21-33. Abstract Reprint Citations Jones K, VanDongen HMA and VanDongen AMJ, 2002, The M3 segment is a transduction element coupling ligand binding to channel opening in the NMDA receptor, J. Neurosci. 22: 2044-2053. Abstract Reprint Citations Persaud-Sawin D-ANW, VanDongen AMJ, and Boustany R-MN, 2002, Motifs within the CLN3 protein: modulation of cell growth rates and apoptosis, Hum. Mol. Genet. 11: 2129-2142. Citations Reprint VanDongen AMJ, 2004, K channel gating by an affinity-switching selectivity filter, Proc. Natl. Acad. Sci. USA 101: 3248-3252. Abstract Reprint Citations. VanDongen AMJ and VanDongen HMA, 2005, Effects of mRNA untranslated regions on translational efficiency of NMDA receptor subunits, Neurosignals 13: 194-206. Abstract Citations
Kalbaugh T, VanDongen HMA and VanDongen AMJ, 2004,
Molecular
determinants of affinity and efficacy in the NMDA receptor ligand
binding domains.
Mol.
Pharmacol. 66: 209-219.
VanDongen AMJ, 2004,
Algorithms
for idealizing single channel data,
Meth.
Enzymol. 383: 229-244.
McNamara II JO, VanDongen HMA, VanDongen AMJ, 2004,
Dendritic Protein Transport
Pathways of Mammalian Hippocampal Neurons Visualized with GFP-TGN38,
Mol. Brain Res.
127: 68-78. Barnes AP, Donelson Smith III F, VanDongen HMA, VanDongen AMJ and Milgram SL, 2004, The identification of a second actin-binding region in spinofilin/neurabin II, Mol. Brain Res 105-113. Citations Reprint Persaud-Sawin D-A, McNamara J, Rylova S, VanDongen AMJ, Boustany R-MN, 2004, A galactosyl-ceramide binding domain is involved in trafficking of CLN3 from Golgi to rafts via recycling endosomes, Pediatrics Res. 56: 1-15. Citations Reprint Grigston JC, VanDongen HMA, McNamara JO and VanDongen AMJ, 2005, Translation of integral membrane proteins in distal dendrites of hippocampal neurons, Eur. J. Neurosci. 21: 1457-1468. Citations Reprint Chapman ML and VanDongen AMJ, 2005, K channel subconductance levels result from heteromeric pore conformations, J. Gen. Physiol. 126: 87–103. Citations Reprint Comment Van de Ven TJ, VanDongen HMA and VanDongen AMJ, 2005, The Non-Kinase Phorbol Ester Receptor α1-Chimaerin Binds the NMDA Receptor NR2A Subunit and Regulates Dendritic Spine Density, J. Neurosci. 25: 9488-9496. Citations Reprint Chapman ML, Blanke ML, Krovetz, HS and VanDongen AMJ, 2006, Allosteric effects of external K ions mediated by D378 in the drk1 K channel, Pflügers Arch. Eur. J. Physiol. 415: 776-792. Abstract Citations Reprint Bloomer WAC, VanDongen HMA and VanDongen AMJ, 2007, Activity-regulated cytoskeleton-associated protein Arc/Arg3.1 binds to spectrin and associates with nuclear promyelocytic leukemia (PML) bodies, Brain Res. 1153: 20-33. Abstract Reprint Citations Bloomer WAC, VanDongen HMA and VanDongen AMJ, 2008, Arc/Arg3.1 translation is controlled by convergent N-Methyl-D-aspartate and Gs-coupled receptor signaling pathways, J. Biol. Chem. 283: 582 - 592. Citations Reprint Blanke ML and VanDongen AMJ, 2008, Constitutive activation of the N-Methyl-D-aspartate receptor via cleft-spanning disulfide bonds J. Biol. Chem. 283: 21519 - 21529. Citations Reprint Blanke ML and VanDongen AMJ, 2009, The NR1 M3 domain mediates allosteric coupling in the N-Methyl-D-Aspartate receptor, Mol. Pharmacol. 74: 454-465. Citations Reprint Ju H, Xu J-X and VanDongen AMJ, 2010, Classification of Musical Styles Using Liquid State Machines, WCCI 2010 Int. Joint Conference on Neural Networks. Abstract Reprint R, Kothapalli R, VanDongen AMJ, Swaminathan K AR-SA, 2012, Chemoinformatic identification of novel inhibitors against Mycobacterium tuberculosis L-aspartate α-decarboxylase, PLoS One. 7(3):e33521. Reprint Ferrari S, Mehta B, Muro GD, VanDongen AMJ, and C. Henriquez C, 2008, Biologically realizable reward-modulated Hebbian training for spiking neural networks, Proc. Int. Joint Conf. Neural Networks (IJCNN), pp. 1781–1787. Reprint Maheswaranathan N, Ferrari S, VanDongen AMJ and Henriquez CS, 2012, Emergent bursting and synchrony in computer simulations of neuronal cultures, Front. Comput. Neurosci. 6:15. Reprint Fu Y, Chin LK, Bourouina T, Liu AQ and VanDongen AMJ, 2012, Nuclear deformation during breast cancer cell transmigration, Lab-on-a-Chip 12:3778-90. Reprint Zhang Z, Foderaro G, Henriquez C, VanDongen AMJ and Ferrari S, 2012, A radial basis function spike model for indirect learning via integrate-and-fire sampling and reconstruction techniques, Adv. Artificial Neural Systems doi:10.1155/2012/713581. Reprint Ju H, Xu J-X, Chong E, and VanDongen AMJ, 2013, Effects of synaptic connectivity on Liquid State Machine performance, Neural Networks 38: 39-51. Reprint Dranias MR, Ju H, Rajaram E, and VanDongen AMJ, 2013, Short-term memory in networks of dissociated cortical neurons, J. Neurosci. 33: 1940-55. Reprint Wee CL, Teo S, Oey NE, Wright GD, VanDongen HMA and VanDongen AMJ, 2014, Nuclear Arc interacts with the histone acetyltransferase Tip60 to modify H4K12 acetylation, eNeuro 0019-14.2014. Reprint Oey NE, Leung, H-W, Ehzilarasan E, Zhou L, Beureman RW, VanDongen HMA, and VanDongen AMJ, 2015, A neuronal activity-dependent dual function chromatin-modifying complex regulates Arc expression, eNeuro 0020-14.2015. Reprint Dranias MR, Westover MB, Cash S, VanDongen AMJ, 2015, Stimulus information stored in lasting active and hidden network states is destroyed by network bursts, Front. Intergr. Neurosci. 9: 14. Reprint Ju H, Dranias MR, Banumurthy G, and VanDongen AMJ, 2015, Spatio-temporal memory is an intrinsic property of networks of dissociated cortical neurons, J. Neurosci. 35:4040-4051. Reprint Ma D, Yoon S-I, Yang C-H, Marcy G, Zhao N, Leong W-Y, Ganapathy V, Han J, Van Dongen AMJ, Hsu K-S, Ming G-L, Augustine GJ and Goh ELK, 2015, Rescue of methyl-CpG binding protein 2 dysfunction-induced defects in newborn neurons by pentobarbital, Neurotherapeutics 10.1007/ s13311-015-0343-0. Zhao N, Ma D, Leong WY, Han J, VanDongen AMJ, Chen T, and Goh ELK, 2015, The methyl-CpG-binding domain (MBD) is crucial for MeCP2’s dysfunction-induced defects in adult newborn neurons, Front. Cell. Neurosci. 9: 158. Oey NE, Leung HW, Ehzilarasan E, Zhou L, Beuerman RW, VanDongen HMA and Dongen AMJ, 2015, A neuronal activity-dependent dual function chromatin-modifying complex regulates Arc expression, eNeuro 0020-14.2015. Ju H, Dranias MR. Banumurthy G and VanDongen AMJ, 2015, Spatio-termporal memory is an intrinsic property of networks of dissociated cortical neurons, J. Neurosci. 35(9): 4040-4051. Samuel GS, Oey NE, Choo M, Ju H, Chan WY, Kok S, Ge Y, VanDongen AMJ and Ng YS, 2016, Combining levodopa and virtual reality-based therapy for the rehabilitation of upper limb acute stroke: pilot study part II, Singapore Med. J. 2016: 1025. Tie HC, Mahajan D, Chen B, Cheng L, VanDongen AMJ and Lu L, 2016, A novel imaging method for quatitative Golgi localization reveals differential intra-Golgi trafficking of secretopry cargoes, Mol. Biol. Cell 27(5): 848-861. Lin L, Goke J, Dranias MR, VanDongen AMJ and Stanton LW, 2016, Molecular features underlying neurodegeneration identified through in vitro modeling of genetically diverse Parkinson's diesease patients, Cell Reports 15(11): 2411-2426. Poon VY, Gu M, VanDongen AMJ and Fivaz M, 2016, miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1, BMC Genomics 117(1):777. Zhang X, Ju H, Penney TB and VanDongen AMJ , 2017, Familiarity detection is an intrinsic property of cortical microcircuits with bidirectional plasticity, eNeuro 0361.16-2017 . |
Books |
VanDongen AMJ, 2008, Biology of the NMDA receptor, Frontiers in Neuroscience, Taylor and Francis CCR Press, Boca Raton, FL, USA |
Book Chapters |
VanErp MG and VanDongen AMJ, 1987, Reduction of excitability and blockage of sodium and potassium channels by valproate, in: Advances in Epileptology, Vol 16, eds. Wolf P, Dam M, Janz D and Dreifuss FE, Raven Press, New York, p. 487-490. Birnbaumer L, Mattera R, Yatani A, Codina J, VanDongen AMJ and Brown AM, 1989, Recent advances in the understanding of multiple roles of G proteins in coupling of receptors to ionic channels and other effectors, in: "ADP-ribosylating toxins and G proteins: insights into signal transduction", Moss J and Vaughan M, eds. Birnbaumer L, VanDongen AMJ, Codina J, Yatani A, Mattera R, Graf R and Brown AM, 1989, Identification of G protein-gated and G protein-modulated ionic channels. Molecular basis for G protein action, Soc. Gen. Physiol. Ser. 44: 18-54, Armstrong CM and Oxford GS, eds., The Rockefeller Univ. Press, N.Y. Birnbaumer L, Yatani A, VanDongen AMJ, Graf R, Codina J, Okabe K, Mattera R and Brown AM, 1990, G protein coupling of receptors to ionic channels and other effector systems. in: "G proteins and Signal transduction", Soc. Gen. Physiol. Ser. 45: 169-183, Nathanson NM and Harden TK eds., Rockefeller University Press, New York. Brown AM, Yatani A, VanDongen AMJ, Kirsch GE, Codina J and Birnbaumer L, 1990, Networking ionic channels by G proteins, in: "G proteins and Signal transduction", Soc. Gen. Physiol. Series 45: 1-9, Nathanson NM and Harden TK eds., Rockefeller University Press, New York. Codina J, Yatani A, VanDongen AMJ, Padrell E, Carty D, Mattera R, Brown AM, Iyengar R and Birnbaumer L, 1990, Receptor-effector coupling by Pertussis toxin substrates. Studies with recombinant and native G-protein a subunits, in: "G proteins", Iyengar R and Birnbaumer L, eds., Academic Press, Florida, Orlando. VanDongen HMA and VanDongen AMJ, 1997, Determination of Membrane Topology of Glutamate Receptors, in: "Methods in Molecular Biology: NMDA Receptor Protocols", Li, M. ed., Humana Press, Totowa, New Jersey.
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Editorials, Positions, and Background Papers |
VanDongen AMJ, 1992, Structure and function of ion channels: a hole in four, Comments in Theor. Biol. 2(6): 429-451. Birnbaumer L, Yatani A, VanDongen AMJ, Graf R, Okabe K, Mattera R and Brown AM, 1990, G protein coupling of receptors to ionic channels and other effector systems, Br. J. Clin. Pharmacol. 30: 13S-22S. |